Evidence map›Paper›PMID 35258329›Full record

ArticlemBio2022

Gonococcal Clinical Strains Bearing a Common

Julio C Ayala, Matthew W Schmerer, Ellen N Kersh, Magnus Unemo, William M Shafer

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Frontiers in cellular and infection microbiology · 2025
    Review
  3. Article
  4. PotentmSphere · 2022
    Article
  5. Transcriptional regulation of theMicrobiology (Reading, England) · 2022
    Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Julio C AyalaDepartment of Microbiology and Immunology, Emory University School of Medicinegrid.471395.d, Atlanta, Georgia, USA.ORCID 0000-0001-9998-3091
Matthew W SchmererSTD Laboratory Reference and Research Branch, Division of STD Prevention, NCHHSTP, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.ORCID 0000-0002-6756-1756
Ellen N KershSTD Laboratory Reference and Research Branch, Division of STD Prevention, NCHHSTP, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.ORCID 0000-0003-3819-0324
Magnus UnemoWHO Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, Department of Laboratory Medicine, Microbiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
William M ShaferDepartment of Microbiology and Immunology, Emory University School of Medicinegrid.471395.d, Atlanta, Georgia, USA.ORCID 0000-0001-9303-8777
Centers for Disease Control and Prevention · USEmory University · USÖrebro University · SE

Funding

GONOCOCCI: GENETICS OF RESISTANCE TO PMN PROTEINSR01AI021150 · NIAID · EMORY UNIVERSITY · PI SHAFER, WILLIAM MAURICE · 1985 to 2025
$5.5M
Gonococci: Genetics of Resistance to PMN ProteinsR37AI021150 · NIAID · EMORY UNIVERSITY · PI SHAFER, WILLIAM MAURICE · 2010 to 2019
$3.9M
BLRD Research Career Scientist Award ApplicationIK6BX005390 · VA · VETERANS HEALTH ADMINISTRATION · PI William Maurice Shafer · 2021 to 2026
–
BLRD VA IK6 BX005390HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI021150-36NIAID NIH HHS R01 AI021150NIAID NIH HHS R37 AI021150
6 · The paper itself

Abstract

GdhR is a transcriptional repressor of the virulence factor gene

Indexed as

GonorrheaPolymorphism, Single NucleotideAmino AcidsAnimalsAnti-Bacterial AgentsBacterial ProteinsDNAFemaleMiceMutationNeisseria gonorrhoeaeRepressor ProteinsUnited StatesVirulenceAmino AcidsAnti-Bacterial AgentsBacterial ProteinsDNARepressor Proteinsantibiotic resistancegdhRlctPmtrRNeisseria gonorrhoeae

Identifiers

PMID35258329
PMCPMC9040798
OpenAlexW4220871064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.