Evidence map›Paper›PMID 35258136›Full record

ReviewJournal of cardiovascular electrophysiology2022

Artificial intelligence and atrial fibrillation.

Ojasav Sehrawat, Anthony H Kashou, Peter A Noseworthy

Abstract readReview
In one paragraph

Review in Journal of cardiovascular electrophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Systematic, randomized atrial fibrillation screening using detailed phenotyping with a risk prediction model combined with patch electrocardiogram in a Swedish population aged 65 years or older: the CONSIDERING-AF trial.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ojasav SehrawatDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-6254-0104
Anthony H KashouDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-1352-0174
Peter A NoseworthyDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-4308-0456

Funding

CARDIOVASOLOGYT32HL007111 · NHLBI · MAYO CLINIC ROCHESTER · PI Barry A. Borlaug · 1985 to 2026
$8.7M
Optimizing stroke prevention for older adults with atrial fibrillation: Towards rigorous evaluation and judicious application of a new deviceR01AG062436 · NIA · MAYO CLINIC ROCHESTER · PI NOSEWORTHY, PETER A, YAO, XIAOXI · 2020 to 2024
$2.5M
Pairing Observational and Patient-level Clinical Trial Data to Assess Cardiovascular Risk Reduction with Catheter Ablation for Atrial FibrillationR21HL140205 · NHLBI · MAYO CLINIC ROCHESTER · PI NOSEWORTHY, PETER A, YAO, XIAOXI · 2017 to 2018
$256k
NHLBI NIH HHS R21 HL140205NHLBI NIH HHS T32 HL007111NIA NIH HHS R01 AG062436
6 · The paper itself

Abstract

backgroundIn the context of atrial fibrillation (AF), traditional clinical practices have thus fallen short in several domains, such as identifying patients at risk of incident AF or patients with concomitant undetected paroxysmal AF. Novel approaches leveraging artificial intelligence have the potential to provide new tools to deal with some of these old problems.

aimsTo discuss the roles of artificial intelligence (AI)-enabled electrocardiogram (ECG) pertaining to AF, potential roles of deep learning (DL) models in the context of current knowledge gaps, as well as limitations of these models. MATERIALS &

methodsAn extensive search and review of the currently available literature on the topics.

resultsOne key area where DL models can translate to better patient outcomes is through automated ECG interpretation. Challenges with regards to the benefits and harms of AF screening remain. In this context, a unique model was developed to detect underlying hidden AF from sinus rhythm. DISCUSSION: Knowledge gaps remain regarding the best ways to monitor patients with embolic stroke of undetermined source (ESUS) and identifying those who would benefit most from oral anticoagulation. The AI-enabled AF model is one potential way to tackle this complex problem as it could be used to identify a subset of high-risk ESUS patients likely to benefit from empirical oral anticoagulation. The role of DL models assessing AF burden from long-duration ECG data is also discussed as a way of guiding management. There is a trend towards the use of consumer-grade wristbands and watches to detect AF from photoplethysmography data. However, ECG currently remains the gold standard to detect arrythmias including AF. Lastly, the role of adequate external validation of the models and clinical trials to study true performance is discussed.

conclusionAlgorithms using AI to interpret ECGs in various new ways have been developed. While still, much work needs to be done, these technologies have shown enormous potential in a short span of time. With further advancements and continuous research, these novel ways of interpretation may well become part of everyday clinical workflow.

Indexed as

Atrial FibrillationAlgorithmsAnticoagulantsArtificial IntelligenceElectrocardiographyHumansAnticoagulantsartificial intelligenceatrial fibrillationconvolutional neural networkdeep learningdeep neural networkECGphotoplethysmography

Identifiers

PMID35258136
PMCPMC9717694

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.