Evidence map›Paper›PMID 35258122›Full record

ArticleJournal of leukocyte biology2022

Characterization of memory T cell subsets and common γ-chain cytokines in convalescent COVID-19 individuals.

Anuradha Rajamanickam, Nathella Pavan Kumar, Arul Nancy Pandiaraj, Nandhini Selvaraj, Saravanan Munisankar, Rachel Mariam Renji, Vijayalakshmi Venkataramani, Manoj Murhekar, Jeromie Wesley Vivian Thangaraj, Santhosh Kumar Muthusamy and 6 more

Abstract read
In one paragraph

Article in Journal of leukocyte biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. T Regulatory Cell Subsets Do Not Restore for One Year After Acute COVID-19.International journal of molecular sciences · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Transient and durable T cell reactivity after COVID-19.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Anuradha RajamanickamICMR-National Institute for Research in Tuberculosis-International Center for Excellence in Research, Chennai, India.
Nathella Pavan KumarICMR-National Institute for Research in Tuberculosis, Chennai, India.
Arul Nancy PandiarajICMR-National Institute for Research in Tuberculosis-International Center for Excellence in Research, Chennai, India.
Nandhini SelvarajICMR-National Institute for Research in Tuberculosis-International Center for Excellence in Research, Chennai, India.
Saravanan MunisankarICMR-National Institute for Research in Tuberculosis-International Center for Excellence in Research, Chennai, India.
Rachel Mariam RenjiICMR-National Institute for Research in Tuberculosis-International Center for Excellence in Research, Chennai, India.
Vijayalakshmi VenkataramaniICMR-National Institute for Research in Tuberculosis-International Center for Excellence in Research, Chennai, India.
Manoj MurhekarNational Institute of Epidemiology (ICMR), Near Ambattur, Ayapakkam, Chennai, India.
Jeromie Wesley Vivian ThangarajNational Institute of Epidemiology (ICMR), Near Ambattur, Ayapakkam, Chennai, India.
Santhosh Kumar MuthusamyNational Institute of Epidemiology (ICMR), Near Ambattur, Ayapakkam, Chennai, India.
Girish Kumar Chethrapilly PurushothamanNational Institute of Epidemiology (ICMR), Near Ambattur, Ayapakkam, Chennai, India.
Tarun BhatnagarNational Institute of Epidemiology (ICMR), Near Ambattur, Ayapakkam, Chennai, India.
Manickam PonnaiahNational Institute of Epidemiology (ICMR), Near Ambattur, Ayapakkam, Chennai, India.
Sabarinathan RamasamyNational Institute of Epidemiology (ICMR), Near Ambattur, Ayapakkam, Chennai, India.
Saravanakumar VelusamyNational Institute of Epidemiology (ICMR), Near Ambattur, Ayapakkam, Chennai, India.
Subash BabuICMR-NIRT-International Center for Excellence in Research, Chennai, India.

Funding

India International Center for Excellence in ResearchZIAAI001065 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NUTMAN, THOMAS · 2009 to 2025
$19.0M
6 · The paper itself

Abstract

T cells are thought to be an important correlates of protection against SARS-CoV2 infection. However, the composition of T cell subsets in convalescent individuals of SARS-CoV2 infection has not been well studied. The authors determined the lymphocyte absolute counts, the frequency of memory T cell subsets, and the plasma levels of common γ-chain in 7 groups of COVID-19 individuals, based on days since RT-PCR confirmation of SARS-CoV-2 infection. The data show that both absolute counts and frequencies of lymphocytes as well as, the frequencies of CD4

Indexed as

COVID-19CytokinesMemory T CellsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesConvalescenceHumansImmunologic MemoryInterleukin-15Interleukin-2Interleukin-7RNA, ViralSARS-CoV-2T-Lymphocyte SubsetsCytokinesInterleukin-15Interleukin-2Interleukin-7RNA, ViralCD4+ T cell subsetsCD8+ T cell subsetsCOVID-19, acute and convalescent COVID-19Memory T cell subsets

Identifiers

PMID35258122
PMCPMC9088480

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.