Evidence map›Paper›PMID 35258042›Full record

Trial reportBiomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia2023

Preoperative nutritional support for patients undergoing elective colorectal cancer surgery - does it really work?

Milan Tesar, Veronika Kozusnikova, Lubomir Martinek, Stefan Durdik, Peter Ihnat

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03930888 (Nutritional Support and Its Influence on the Reduction of Muscle Strength, Muscle Mass and Self-sufficiency in Patients Undergoing Surgical Treatment of Colorectal Cancer), which is not on this map. Cited by 6 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 4 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03930888 completednot on this map

Nutritional Support and Its Influence on the Reduction of Muscle Strength, Muscle Mass and Self-sufficiency in Patients Undergoing Surgical Treatment of Colorectal Cancer

TypeobservationalSponsorUniversity Hospital OstravaRan2019 to 2020Enrolled120ConditionsColorectal CancerArmsDietary supplement
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Milan TesarDepartment of Surgery, University Hospital Ostrava, 17. listopadu 1790, Ostrava 708 52, Czech Republic.
Veronika KozusnikovaDepartment of Surgery, University Hospital Ostrava, 17. listopadu 1790, Ostrava 708 52, Czech Republic.
Lubomir MartinekDepartment of Surgery, University Hospital Ostrava, 17. listopadu 1790, Ostrava 708 52, Czech Republic.
Stefan DurdikDepartment of Oncosurgery, Faculty of Medicine, Commenius University, Spitalska 24, Bratislava 813 72, Slovak Republic.
Peter IhnatDepartment of Surgery, University Hospital Ostrava, 17. listopadu 1790, Ostrava 708 52, Czech Republic.
University Hospital Ostrava · CZUniversity of Ostrava · CZComenius University Bratislava · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study aimed to evaluate the effect of preoperative administration of oral nutritional supplements (ONS) on the self-sufficiency, physical status, and nutritional status of patients undergoing elective colorectal resections.

methodsThis prospective randomized clinical trial was conducted in a single institution. Patients scheduled to undergo colorectal cancer surgery were randomized to either ONS twice per day for 7 days before surgery or no ONS.

resultsWe enrolled 120 patients in the study. The two study groups had comparable hospital stay times and comparable numbers of postoperative complications. Laboratory parameter (albumin and prealbumin) values declined in the postoperative period, but differences between study groups were not significant. The groups had comparable arm circumference measurements, muscle mass and fat proportions, and water weights. Patient self-sufficiency in the postoperative period was comparable between groups (P=0.313). Lower limb force declined after surgery, but differences between the groups were not significant (P=0.579).

conclusionPreoperative administration of ONS to patients undergoing elective colorectal surgery did not reduce postoperative morbidity or enhance recovery. Moreover, patient self-sufficiency, physical status, and nutritional status were not influenced by preoperative ONS. Patients should be properly selected for malnourishment before providing nutritional support to manage costs efficiently.

trial registrationClinicalTrials.gov (NCT03930888).

Indexed as

Colorectal NeoplasmsNutritional SupportDietary SupplementsHumansLength of StayNutritional StatusPostoperative ComplicationsProspective Studiescolorectal cancermalnutritionnutritional supplementspostoperative morbidityself-sufficiency

Identifiers

PMID35258042
OpenAlexW4220698069

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.