Evidence map›Paper›PMID 35257661›Full record

ArticleeLife2022

Ca

Ashok R Nayak, Montserrat Samsó

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Cylindrical Crystallization of CaInternational journal of molecular sciences · 2026
    Review
  3. Article
  4. Characterization of cardiac disease-associated mutations in RyR2 CaAmerican journal of physiology. Cell physiology · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Structural insights into the regulation of RyR1 by S100A1.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Article
  14. Significance of ZnThe journal of physical chemistry. B · 2024
    Article
  15. Interplay between MgNature communications · 2024
    Article
  16. EuBiophysical journal · 2023
    Article
  17. Review
  18. Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ashok R NayakDepartment of Physiology and Biophysics, Virginia Commonwealth University, Richmond, United States.ORCID 0000-0001-9531-5168
Montserrat SamsóDepartment of Physiology and Biophysics, Virginia Commonwealth University, Richmond, United States.ORCID 0000-0002-2788-3283
Virginia Commonwealth University · US

Funding

UVA molecular electron microscopy core for the Mid-Atlantic regionU24GM116790 · NIGMS · UNIVERSITY OF VIRGINIA · PI GALKIN, VITOLD, SAMSO, MONTSERRAT · 2017 to 2021
$2.9M
RyR architecture and gatekeeping of internal calcium storesR01AR068431 · NIAMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI SAMSO, MONTSERRAT · 2017 to 2021
$2.0M
Structure Analysis of Viral Assembly MechanismsR01GM128507 · NIGMS · UNIVERSITY OF VIRGINIA · PI YEAGER, MARK JAY · 2018 to 2019
$1.5M
NIAMS NIH HHS R01 AR068431NIGMS NIH HHS R01 GM128507NIGMS NIH HHS U24 GM116790
6 · The paper itself

Abstract

Activation of the intracellular Ca

Indexed as

CalciumRyanodine Receptor Calcium Release ChannelAnimalsCryoelectron MicroscopyCytosolEF Hand MotifsMammalsRabbitsCalciumRyanodine Receptor Calcium Release Channelcalciumcryo-electron microscopyexcitation-contraction couplinginactivationmolecular biophysicsrabbitryanodine receptorstructural biology

Identifiers

PMID35257661
PMCPMC8947763
OpenAlexW4220801593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.