ArticleAngewandte Chemie (International ed. in English)2022
Digitizing Chemical Synthesis in 3D Printed Reactionware.
Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Solvent-based post-processing to fill layer gaps in FFF-printed polypropylene fluidic chips and their application to flow injection analysis.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026Article
- Article
- ERCAD: A Parametric Reactor Design Tool That Enables Rapid Prototyping and Optimization of Electrochemical Reactors through 3D Printing.ACS central science · 2024Article
- Deductive machine learning models for product identification.Chemical science · 2024Article
- Robotic Modules for the Programmable Chemputation of Molecules and Materials.ACS central science · 2023Review
- 3D-Printing of Capsule Devices as Compartmentalization Tools for Supported Reagents in the Search of Antiproliferative Isatins.Pharmaceuticals (Basel, Switzerland) · 2023Article
- The way to AI-controlled synthesis: how far do we need to go?Chemical science · 2022Review
- Autonomous Chemical Experiments: Challenges and Perspectives on Establishing a Self-Driving Lab.Accounts of chemical research · 2022Article
- Digitizing Chemical Synthesis in 3D Printed Reactionware.Angewandte Chemie (International ed. in English) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Chemistry digitization requires an unambiguous link between experiments and the code used to generate the experimental conditions and outcomes, yet this process is not standardized, limiting the portability of any chemical code. What is needed is a universal approach to aid this process using a well-defined standard that is composed of syntheses that are employed in modular hardware. Herein we present a new approach to the digitization of organic synthesis that combines process chemistry principles with 3D printed reactionware. This approach outlines the process for transforming unit operations into digitized hardware and well-defined instructions that ensure effective synthesis. To demonstrate this, we outline the process for digitizing 3 MIDA boronate building blocks, an ester hydrolysis, a Wittig olefination, a Suzuki-Miyaura coupling reaction, and synthesis of the drug sulfanilamide.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.