Evidence map›Paper›PMID 35257353›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2022

Hypo-Hydroxymethylation of Nobox is Associated with Ovarian Dysfunction in Rat Offspring Exposed to Prenatal Hypoxia.

Changfang Yao, Likui Lu, Yiting Ji, Yingying Zhang, Weisheng Li, Yajun Shi, Jinliu Liu, Miao Sun, Fei Xia

Open access · hybridAbstract read
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Effects of Acute Hypoxic Exposure on Ovarian Function in Female Mice.Reproductive sciences (Thousand Oaks, Calif.) · 2026
    Article
  2. Article
  3. Association between polymorphisms inFrontiers in veterinary science · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Changfang YaoReproductive Medicine Center of the First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Likui LuInstitute for Fetology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Yiting JiReproductive Medicine Center of the First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Yingying ZhangInstitute for Fetology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Weisheng LiInstitute for Fetology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Yajun ShiInstitute for Fetology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Jinliu LiuInstitute for Fetology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Miao SunInstitute for Fetology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. miaosunsuda@163.com.
Fei XiaReproductive Medicine Center of the First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China. 766090173@qq.com.ORCID 0000-0001-5503-2921
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prenatal hypoxia (PH) is a common feature of a suboptimal intrauterine environment affecting the development of fetuses. Whether PH leads to abnormal ovary development is not yet clear. This study investigated ovarian function in offspring exposed to PH and the potential underlying molecular mechanisms. SD female rats (n = 12 per group) at 9 weeks of age were housed in individual cages (21% O

Indexed as

Ovarian DiseasesOvarian FollicleAnimalsEpigenesis, GeneticFemaleFollicular AtresiaHumansHypoxiaPregnancyRatsFetal origins of adult diseaseNewborn ovary homeobox geneOvarianPrenatal hypoxiaTen-eleven translocation

Identifiers

PMID35257353
PMCPMC9005429
OpenAlexW4220840655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.