Evidence map›Paper›PMID 35257302›Full record

ReviewJournal of gastrointestinal cancer2023

Merkel Cell Carcinoma with Gastric Metastasis, a Rare Presentation: Case Report and Literature Review.

Vittorio Durastante, Antonello Conte, Pier Paolo Brollo, Carlo Biddau, Michele Graziano, Vittorio Bresadola

Abstract readReviewCase Reports
PubMed Publisher
In one paragraph

Review in Journal of gastrointestinal cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vittorio DurastanteGeneral Surgery Department, Civil Hospital of Tolmezzo, Udine, Italy. vittorio.durastante@asufc.sanita.fvg.it.
Antonello ConteGeneral Surgery Department, Civil Hospital of Tolmezzo, Udine, Italy.
Pier Paolo BrolloGeneral Surgery Department and Simulation Center, Department of Medicine, Academic Hospital of Udine, University of Udine, Udine, Italy.ORCID http://orcid.org/0000-0001-5943-9737
Carlo BiddauGeneral Surgery Department, Hospital of Pordenone, Pordenone, Italy.
Michele GrazianoGeneral Surgery Department, Hospital of Latisana, Udine, Italy.
Vittorio BresadolaGeneral Surgery Department and Simulation Center, Department of Medicine, Academic Hospital of Udine, University of Udine, Udine, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMerkel cell carcinoma (MCC) is an infrequent, but highly aggressive neuroendocrine neoplasm of the skin with a propensity for recurrence and metastasis. We report a rare case of gastric metastatic localization of this cancer by focusing on the diagnostic, clinical, and surgical approach to the patient. CASE REPORT: Clinical presentation begins with a peripheral lymphadenopathy whose immunohistochemical characterization identifies the lymphatic dissemination of the disease. Gradually, the patient develops a severe anaemic state which requires several blood transfusions and surgical gastric resection to remove a large bleeding lesion of the antral region. The histopathological analysis of the specimen confirms the metastatic origin from MCC, but the primitive lesion remains unknown. DISCUSSION: Since this clinical situation is very rare, we conducted a review of the literature selecting the few cases reported, in order to evaluate the current knowledge on this topic. Metastatic involvement of the stomach from Merkel cell carcinoma is a rare presentation of this disease progression with a frequent delay in formulating the correct diagnosis and in further treatment which may be life-threatening for the patient. As regards the local treatment, there is no specific guideline, and the therapeutic indication should be tailored on the specific case.

Indexed as

Carcinoma, Merkel CellSkin NeoplasmsHumansSkinStomachGastric metastasisGastric surgeryImmunotherapy for cancerMerkel cell carcinomaNeuroendocrine tumors

Identifiers

PMID35257302

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.