ArticleCerebral cortex (New York, N.Y. : 1991)2022
Relationships between interoceptive sensibility and resting-state functional connectivity of the insula in obsessive-compulsive disorder.
Article in Cerebral cortex (New York, N.Y. : 1991), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The relationship between sensory phenomena and interoception across the obsessive-compulsive spectrum: a systematic review.BMC psychiatry · 2025Pooled it
- Reliability and validity of the Chinese version of The University of São Paulo Sensory Phenomena Scale in OCD patients.BMC psychiatry · 2025Article
- Identifying subgroups of urge suppression in Obsessive-Compulsive Disorder using machine learning.Journal of psychiatric research · 2024Article
- Sensory over-responsivity and orbitofrontal cortex connectivity in obsessive-compulsive disorder.Journal of affective disorders · 2024Article
- The Seeking Proxies for Internal States (SPIS) Model of OCD - A Comprehensive Review of Current Findings and Implications for Future Directions.Current neuropharmacology · 2024Review
- Associations Between Suicidality and Interoception in Obsessive-Compulsive Disorder.Journal of obsessive-compulsive and related disorders · 2023Article
- Abnormal resting-state functional connectivity of the insula in medication-free patients with obsessive-compulsive disorder.BMC psychiatry · 2022Article
- Altered Interoceptive Sensibility in Adults With Chronic Tic Disorder.Frontiers in psychiatry · 2022Article
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7 authors.
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Abstract
Patients with obsessive-compulsive disorder (OCD) exhibit abnormality in their subjective perception of internal sensation, a process known as interoceptive sensibility (IS), as well as altered functioning of the insula, a key neural structure for interoception. We investigated the multivariate structure of IS in 77 OCD patients and 53 controls and examined associations of IS with resting-state functional connectivity (FC) of the insula within the OCD group. For each group, principal component analysis was performed on 8 subscales of the Multidimensional Assessment of Interoceptive Awareness assessing putatively "adaptive" and "maladaptive" aspects of IS. Associations between IS components and insula FC in the OCD group were evaluated using seed regions placed in each of 3 subdivisions of the insula (posterior, anterior dorsal, and anterior ventral). Behaviorally, controls showed a 2-component solution broadly categorized into "adaptive" and "maladaptive" IS, while OCD patients exhibited a 3-component solution. The general tendency to notice or be aware of sensation loaded onto an "adaptive" IS component in controls but loaded onto both "adaptive" and "maladaptive" IS components in OCD. Within OCD, insula FC was differentially associated with distinct aspects of IS, identifying network connections that could serve as future targets for the modulation of IS in OCD.
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