Evidence map›Paper›PMID 35257057›Full record

ArticleKidney international reports2022

Kidney Function, Kidney Replacement Therapy, and Mortality in Men and Women.

Sebastian Hödlmoser, Juan Jesus Carrero, Amelie Kurnikowski, Edouard L Fu, Oskar Swartling, Wolfgang C Winkelmayer, Eva S Schernhammer, Manfred Hecking

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Risk of Hospital Readmission among People with CKD: A Population-Based Cohort Study.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  3. Article
  4. Article
  5. Lower access to kidney transplantation for women in France is not explained by comorbidities and social deprivation.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Sebastian HödlmoserDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.
Juan Jesus CarreroDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Amelie KurnikowskiClinical Division of Nephrology & Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Edouard L FuDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Oskar SwartlingClinical Epidemiology Division, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Wolfgang C WinkelmayerSection of Nephrology, Selzman Institute for Kidney Health, Baylor College of Medicine, Houston, Texas, USA.
Eva S SchernhammerDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.
Manfred HeckingClinical Division of Nephrology & Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Karolinska Institutet · SEMedical University of Vienna · ATBaylor College of Medicine · USHarvard University · US

Funding

Austrian Science Fund FWF KLI 754
6 · The paper itself

Abstract

Introduction: Women are more likely to have chronic kidney disease (CKD), compared with men, yet they are less likely to receive dialysis. Whether this sex disparity, which has predominantly been observed in nephrology-referred or CKD-specific cohorts so far, has a biological root cause remains unclear. Methods: We extracted general population data from the Stockholm CREAtinine Measurements project (SCREAM) ( Results: Compared with women, men were significantly more likely to receive KRT (fully adjusted male-to-female csHR for KRT 1.41 [95% CI 1.13-1.76]) but also more likely to experience pre-KRT death (csHR 1.36 [95% CI 1.33-1.38]). Differences between men and women regarding all-cause mortality by eGFR indicated a higher mortality in men at low eGFR values. Conclusion: Our data show that sex differences in CKD outcomes persist even after controlling for important comorbidities and kidney function at baseline. While future studies with a wider range of biological factors are warranted, these data suggest that nonbiological factors may be more important in explaining existing sex disparities in CKD progression and therapy.

Indexed as

kidney replacement therapy initiationmortality in the predialysis stagesex and gender disparitysex/gender differences in nephrology

Identifiers

PMID35257057
PMCPMC8897304
OpenAlexW4200129554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.