ArticleToxicology reports2022
Effect of occupational exposure to lead on serum levels of lipid profile and liver enzymes: An occupational cohort study.
Article in Toxicology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 49 citations in OpenAlex.
- Review
- Article
- Distribution of Toxic and Essential Elements in Autopsy Organs of Subjects Living in South-Eastern Poland.International journal of molecular sciences · 2026Article
- Fibrinogen-to-albumin ratio as a novel biomarker in pneumoconiosis: a retrospective cohort study.International journal of occupational medicine and environmental health · 2026Article
- The Mechanisms of Lead Toxicity in Living Organisms.Journal of xenobiotics · 2025Review
- Detection of reproductive and hematobiochemical biomarkers to evaluate the impact of heavy metal exposure on brick kiln workers.Scientific reports · 2025Article
- Article
- UnderstandingToxicology reports · 2024Review
- Lead Concentrations in Tissues of Pigeons (Toxics · 2024Article
- Estrogen replacement therapy reverses spatial memory loss and pyramidal cell neurodegeneration in the prefrontal cortex of lead-exposed ovariectomized Wistar rats.Current research in toxicology · 2024Article
- Internal blood lead exposure levels in permanent residents of Jiangxi Province and its effects on routine hematological and biochemical indices.Frontiers in public health · 2024Article
- Quercetin as a Dietary Supplementary Flavonoid Alleviates the Oxidative Stress Induced by Lead Toxicity in Male Wistar Rats.Nutrients · 2023Article
- Potential diagnostic biomarkers for lead-induced hepatotoxicity and the role of synthetic chelators and bioactive compounds.Toxicology research · 2023Review
- The association between blood heavy metals level and sex hormones among postmenopausal women in the US.Frontiers in endocrinology · 2023Article
- Aluminum, Arsenic, Beryllium, Cadmium, Chromium, Cobalt, Copper, Iron, Lead, Mercury, Molybdenum, Nickel, Platinum, Thallium, Titanium, Vanadium, and Zinc: Molecular Aspects in Experimental Liver Injury.International journal of molecular sciences · 2022Review
- Role of Ape1 in Impaired DNA Repair Capacity in Battery Recycling Plant Workers Exposed to Lead.International journal of environmental research and public health · 2022Article
- Epidemiological characteristics of occupational chemical poisonings in Zhejiang, China from 2006 to 2020: A descriptive analysis.Frontiers in public health · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was performed to know the effects of chronic lead exposure on serum lipids, lipoproteins, and liver enzymes in a cohort study among of lead mine workers. We followed of 200 Iranian workers for 3- years (2018-2020), 100 of them with known occupational exposure to lead thorough their work in lead mine while the others 100 were with no such exposure. Blood lead level (BLL), serum lipids, lipoproteins, and liver enzymes of the exposure group for 3- years were measured and compared with those attained in the non-exposed workers. The BLL levels of the lead-mine workers were higher than with recommended level and the non-exposed group (24.15 and 6.35 µg/dL, respectively). The findings indicated a positive and significant relationship between BLL and lactate dehydrogenase, aspartate transaminase, alkaline phosphatase, alanine transaminase, and bilirubin levels (P < 0.01). Also while we found a negative and significant correlation between BLL and triglyceride, total protein, albumin, and globulin levels (P < 0.01). This report depicted that chronic lead exposure is a risk factor for hematological, liver, and cardiovascular diseases. Despite the fact that the level of liver function parameters was in the normal range, the results of 3- years follow-up show a significant relationship between BLL and alteration of biochemical parameters levels.
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