ArticleScientific reports2022
Short term feeding of industrial hemp with a high cannabidiolic acid (CBDA) content increases lying behavior and reduces biomarkers of stress and inflammation in Holstein steers.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 43 citations in OpenAlex.
- Physiological effect and pharmacokinetic evaluation of combined oral administration of cannabidiolic acid and cannabigerolic acid in dogs.Frontiers in veterinary science · 2026Article
- Tissue residue depletion of cannabinoids in cattle administered industrial hemp inflorescence.Scientific reports · 2025Article
- Field safety and efficacy study with a cannabidiol/cannabidiol acid-rich hemp paste in cats with osteoarthritic pain.Journal of feline medicine and surgery · 2025Article
- Replacing Soybean Meal with Hemp Leaves with Very Low THC Content in the Diet for Dairy Cows: Impact on Digestibility, Nitrogen Use Efficiency and Energy Metabolism.Animals : an open access journal from MDPI · 2025Article
- Cannabinoid Distribution and Clearance in Feeding Spent Hemp Biomass to Dairy Cows and the Potential Exposure to ΔJournal of agricultural and food chemistry · 2025Article
- Replacing Soybean Meal with Hemp Leaves in a Dairy Cow Diet: Plasma Antioxidative Capacity, Inflammatory Parameters and Milk Constituents.Animals : an open access journal from MDPI · 2025Article
- Use of industrial hemp byproducts in ruminants: a review of the nutritional profile, animal response, constraints, and global regulatory environment.Journal of cannabis research · 2025Review
- Plasma cannabinoid concentrations and transference during long-term industrial hemp administration in cattle.Journal of animal science · 2025Article
- Limited 12-hour pharmacokinetic assessment of CBD and CBDA isolates compared to their full-spectrum extracts in healthy adult beagles.Frontiers in veterinary science · 2025Article
- Pilot study: impacts of cannabinoids from industrial hemp and repeated transportation events on cattle health and immune status.Translational animal science · 2025Article
- Is hemp (Translational animal science · 2025Article
- The Pharmacokinetics of ΔAnimals : an open access journal from MDPI · 2024Article
- Endocannabinoid system and phytocannabinoids in the main species of veterinary interest: a comparative review.Veterinary research communications · 2024Review
- Effects of Hemp-Derived Cannabidiol Supplementation on Blood Variables, Carcass Characteristics, and Meat Quality of Goats.Animals : an open access journal from MDPI · 2024Article
- Partially substituting alfalfa hay with hemp forage in the diet of goats improved feed efficiency, ruminal fermentation pattern and microbial profiles.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Comparison of the Effects of Essential Oils fromInternational journal of molecular sciences · 2024Article
- Comparative Study of Gas and Liquid Chromatography Methods for the Determination of Underivatised Neutral and Acidic Cannabinoids and Cholesterol.Molecules (Basel, Switzerland) · 2024Article
- Cannabidiol can affect morphology, morphometry, enzymatic and microbial activity of rabbit digestive system.Journal of animal science · 2024Article
- Role of cannabidiolic acid or the combination of cannabigerol/cannabidiol in pain modulation and welfare improvement in horses with chronic osteoarthritis.Frontiers in veterinary science · 2024Article
- Pharmacokinetics and tolerability of single-dose enteral cannabidiol and cannabidiolic acid rich hemp in horses (Frontiers in veterinary science · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Industrial hemp (IH) is defined as Cannabis sativa containing < 0.3% delta-9 tetrahydrocannabinol (THC) and was legalized in the 2018 Farm Bill. The impact of cannabinoids in IH fed to livestock, especially after repeat exposure, has not been thoroughly investigated. Sixteen male castrated Holstein cattle weighting (± SD) 447 ± 68 kg were enrolled onto the study. Cattle were allocated into two treatment groups either receiving IH (HEMP, n = 8) or a control (CNTL, n = 8). Cattle in the HEMP group were fed 25 g IH mixed in 200 g of grain once a day for 14 days to target a daily dose of 5.5 mg/kg of cannabidiolic acid (CBDA). Behavior was continuously monitored with accelerometers and blood samples were collected at predetermined time points for plasma cannabinoid, serum cortisol, serum haptoglobin, liver enzymes, serum amyloid A, and prostaglandin E
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