Evidence map›Paper›PMID 35256657›Full record

ArticleScientific reports2022

Low correlation between Ki67 assessed by qRT-PCR in Oncotype Dx score and Ki67 assessed by Immunohistochemistry.

Zohair Selmani, Chloé Molimard, Alexis Overs, Fernando Bazan, Loic Chaigneau, Erion Dobi, Nathalie Meneveau, Laura Mansi, Marie-Justine Paillard, Guillaume Meynard and 7 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Zohair Selmani *Department of Oncobiology, University Hospital of Besançon, Besançon, France. zselmani@chu-besancon.fr.
Chloé Molimard *Department of Anatomopathology, University Hospital of Besançon, Besançon, France.
Alexis OversDepartment of Oncobiology, University Hospital of Besançon, Besançon, France.
Fernando BazanDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.
Loic ChaigneauDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.
Erion DobiDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.
Nathalie MeneveauDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.
Laura MansiDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.
Marie-Justine PaillardDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.
Guillaume MeynardDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.
Julien ViotDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.
Marie-Paule AlgrosDepartment of Anatomopathology, University Hospital of Besançon, Besançon, France.
Christophe BorgDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.
Jean-Paul FeugeasDepartment of Oncobiology, University Hospital of Besançon, Besançon, France.
Xavier PivotICANS, Strasbourg, France.
Jean-Luc PrétetDepartment of Oncobiology, University Hospital of Besançon, Besançon, France.
Elsa CurtitDepartment of Medical Oncology, University Hospital of Besançon, Besançon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancers expressing high levels of Ki67 are associated with poor outcomes. Oncotype DX test was designed for ER+/HER2- early-stage breast cancers to help adjuvant chemotherapy decision by providing a Recurrent Score (RS). RS measures the expression of 21 specific genes from tumor tissue, including Ki67. The primary aim of this study was to assess the agreement between Ki67

Indexed as

Breast NeoplasmsReceptors, EstrogenBiomarkers, TumorErb-b2 Receptor Tyrosine KinasesFemaleGene Expression ProfilingHumansImmunohistochemistryKi-67 AntigenNeoplasm Recurrence, LocalPrognosisReverse Transcriptase Polymerase Chain ReactionRNABiomarkers, TumorErb-b2 Receptor Tyrosine KinasesKi-67 AntigenReceptors, EstrogenRNA

Identifiers

PMID35256657
PMCPMC8901910

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.