Evidence map›Paper›PMID 35256599›Full record

ArticleNPJ breast cancer2022

Impact of a randomized weight loss trial on breast tissue markers in breast cancer survivors.

Christina M Dieli-Conwright, Maura Harrigan, Brenda Cartmel, Anees Chagpar, Yalai Bai, Fang-Yong Li, David L Rimm, Lajos Pusztai, Lingeng Lu, Tara Sanft and 1 more

Open access · goldAbstract read
In one paragraph

Article in NPJ breast cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Is Adipose Tissue Inflammation the Culprit of Obesity-Associated Comorbidities?Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Christina M Dieli-ConwrightDivision of Population Sciences, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. ChristinaM_Dieli-Conwright@DFCI.Harvard.edu.ORCID http://orcid.org/0000-0001-9093-7259
Maura HarriganYale School of Public Health, New Haven, CT, USA.
Brenda CartmelYale School of Public Health, New Haven, CT, USA.
Anees ChagparYale Cancer Center, New Haven, CT, USA.
Yalai BaiYale School of Medicine, New Haven, CT, USA.
Fang-Yong LiYale Center for Analytic Sciences, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-3171-7592
David L RimmYale Cancer Center, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-5820-4397
Lajos PusztaiYale Cancer Center, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-9632-6686
Lingeng LuYale School of Public Health, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-9871-0809
Tara SanftYale Cancer Center, New Haven, CT, USA.
Melinda L IrwinYale School of Public Health, New Haven, CT, USA.
Yale Cancer Center · USYale University · USHarvard University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Transdisciplinary Research in Energetics and Cancer (TREC) Training GrantR25CA203650 · NCI · YALE UNIVERSITY · PI IRWIN, MELINDA L · 2016 to 2025
$2.9M
NCATS NIH HHS UL1 TR001863NCI NIH HHS R25 CA203650
6 · The paper itself

Abstract

Few trials have examined the effect of lifestyle behavioral interventions on tissue markers in patients with cancer. The purpose of this study was to examine the feasibility and impact of a 6-month weight loss intervention on breast tissue and serum biomarkers in women with breast cancer. Fifty-one women who completed breast cancer treatment and had a BMI ≥ 25.0 kg/m

Identifiers

PMID35256599
PMCPMC8901848
OpenAlexW4220879352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.