Evidence map›Paper›PMID 35256490›Full record

ArticleSaudi medical journal2022

Phenotypic and genotypic detection of carbapenemase production among gram negative bacteria isolated from hospital acquired infections.

Sreeja K Vamsi, Rama S Moorthy, Mary N Hemiliamma, Rama B Chandra Reddy, Deepak J Chanderakant, Shravani Sirikonda

Open access · diamondAbstract read
In one paragraph

Article in Saudi medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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  16. Clinical and Molecular Profile of Carbapenem ResistantInfection and drug resistance · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sreeja K VamsiFrom the Department of Microbiology (Sreeja Vamsi); Manipal Academy of Higher Education; Karnataka, from the Department of Microbiology (Moorthy); Palamur Biosciences Pvt. Ltd., from the Department of Microbiology (Hemiliamma, Chandra Reddy); from the Department of Community Medicine (chanderakant); and from the Department of Microiology (Sirikonda); Sri Venkata Sai Medical College and Hospital, Telangana, India.
Rama S MoorthyFrom the Department of Microbiology (Sreeja Vamsi); Manipal Academy of Higher Education; Karnataka, from the Department of Microbiology (Moorthy); Palamur Biosciences Pvt. Ltd., from the Department of Microbiology (Hemiliamma, Chandra Reddy); from the Department of Community Medicine (chanderakant); and from the Department of Microiology (Sirikonda); Sri Venkata Sai Medical College and Hospital, Telangana, India.
Mary N HemiliammaFrom the Department of Microbiology (Sreeja Vamsi); Manipal Academy of Higher Education; Karnataka, from the Department of Microbiology (Moorthy); Palamur Biosciences Pvt. Ltd., from the Department of Microbiology (Hemiliamma, Chandra Reddy); from the Department of Community Medicine (chanderakant); and from the Department of Microiology (Sirikonda); Sri Venkata Sai Medical College and Hospital, Telangana, India.
Rama B Chandra ReddyFrom the Department of Microbiology (Sreeja Vamsi); Manipal Academy of Higher Education; Karnataka, from the Department of Microbiology (Moorthy); Palamur Biosciences Pvt. Ltd., from the Department of Microbiology (Hemiliamma, Chandra Reddy); from the Department of Community Medicine (chanderakant); and from the Department of Microiology (Sirikonda); Sri Venkata Sai Medical College and Hospital, Telangana, India.
Deepak J ChanderakantFrom the Department of Microbiology (Sreeja Vamsi); Manipal Academy of Higher Education; Karnataka, from the Department of Microbiology (Moorthy); Palamur Biosciences Pvt. Ltd., from the Department of Microbiology (Hemiliamma, Chandra Reddy); from the Department of Community Medicine (chanderakant); and from the Department of Microiology (Sirikonda); Sri Venkata Sai Medical College and Hospital, Telangana, India.
Shravani SirikondaFrom the Department of Microbiology (Sreeja Vamsi); Manipal Academy of Higher Education; Karnataka, from the Department of Microbiology (Moorthy); Palamur Biosciences Pvt. Ltd., from the Department of Microbiology (Hemiliamma, Chandra Reddy); from the Department of Community Medicine (chanderakant); and from the Department of Microiology (Sirikonda); Sri Venkata Sai Medical College and Hospital, Telangana, India.
Institute of Medical Sciences · INSri Venkateswara Medical College and Ruia Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo identify the carbapenemase producing Gram-negative bacteria (GNB) by phenotypic methods and to confirm the presence of resistant genes using real-time polymerase chain reaction (PCR).

methodsThis was a prospective study carried out at the Department of Microbiology, Sri Venkata Sai Medical College and Hospital, Mahabubnagar, India, from March 2018-2021. All samples were screened for carbapenem resistance by disc diffusion method and the VITEK

resultsAmong the 1093 Gram-negative bacilli identified, 220 (17.0%) were resistant to carbapenems by both tested methods. Carbapenemase detection using the RAPIDEC

conclusionThis study suggests routine carbapenem resistance testing among multi-drug resistant-GNBs, as most of these infections occur in hospitals. In addition, there is a possibility that these highly antibiotic-resistant genes could spread to other bacteria resulting in further dissemination.

Indexed as

Bacterial Proteinsbeta-LactamasesAnti-Bacterial AgentsGram-Negative BacteriaHospitalsHumansMicrobial Sensitivity TestsProspective StudiesAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasescarbapenemaseantibacterial agentsbeta-lactamasescarbapenemsdrug resistancemicrobial

Identifiers

PMID35256490
PMCPMC9280532
OpenAlexW4220677902

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.