ArticleAddiction science & clinical practice2022
Six-month outcomes of the HOPE smartphone application designed to support treatment with medications for opioid use disorder and piloted during an early statewide COVID-19 lockdown.
Article in Addiction science & clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Effects of Bundling Medication for Opioid Use Disorder With an mHealth Intervention Targeting Addiction: A Randomized Clinical Trial.The American journal of psychiatry · 2024Trial
- Digital mental health tools for use by individuals in opioid use recovery: An academic scoping and commercial review.PLOS digital health · 2026Article
- Development of the Healthy Women Intervention to Increase Women's Engagement in Medication Treatment for Opioid Use Disorder: Mixed Methods, User-Centered Design Approach.JMIR formative research · 2026Article
- A Complex Digital Health Intervention to Support People With HIV: Organizational Readiness Survey Study and Preimplementation Planning for a Hybrid Effectiveness-Implementation Study.Journal of medical Internet research · 2026Article
- Engaging veterans in the development of mobile health interventions to support medication treatment for opioid use disorder.Frontiers in digital health · 2026Article
- Telehealth and Pharmacotherapy: The Role of Synchronous and Novel Asynchronous Digital Health Tools in Psychiatry.Pharmaceutical medicine · 2025Review
- Patterns of mHealth Engagement and Identification of Facilitators and Barriers to Mobile Health Applications for People Who Use Opioids.International journal of environmental research and public health · 2025Article
- Mental health behaviors and suicide risk among White and Black adults with Opioid Use Disorder.Social science & medicine (1982) · 2025Article
- Digital Psychosocial Interventions Tailored for People in Opioid Use Disorder Treatment: Scoping Review.Journal of medical Internet research · 2025Article
- Sociodemographic Differences in Logins and Engagement With the Electronic Health Coach Messaging Feature of a Mobile App to Support Opioid and Stimulant Use Recovery: Results From a 1-Month Observational Study.JMIR mHealth and uHealth · 2025Observational
- What smartphone apps exist to support recovery from opioid use disorder? A content analysis of publicly available opioid-related smartphone apps.Addiction science & clinical practice · 2025Article
- Fathers' Cocaine Use and Parent-Child Feeding Interactions.Journal of clinical medicine · 2025Article
- Psychosocial Outcomes Associated with Mobile Health App Use among Medicaid Recipients who Use Substances.Journal of social work practice in the addictions · 2025Article
- Evaluating a mobile app's effects on depression and anxiety in medication-treated opioid use disorder.Npj mental health research · 2024Article
- Users' Acceptability and Perceived Efficacy of mHealth for Opioid Use Disorder: Scoping Review.JMIR mHealth and uHealth · 2024Article
- Development and Evaluation of a Digital App for Patient Self-Management of Opioid Use Disorder: Usability, Acceptability, and Utility Study.JMIR formative research · 2024Article
- Mobile health supported multi-domain recovery trajectories after major arthroplasty or spine surgery: a pilot feasibility and usability study.BMC musculoskeletal disorders · 2023Observational
- Principal component regression analysis of familial psychiatric histories and suicide risk factors among adults with opioid use disorder.Journal of psychiatric research · 2023Article
- Review
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMorbidity and mortality related to opioid use disorder (OUD) in the U.S. is at an all-time high. Innovative approaches are needed to address gaps in retention in treatment with medications for opioid use disorder (MOUD). Mobile health (mHealth) approaches have shown improvement in engagement in care and associated clinical outcomes for a variety of chronic diseases, but mHealth tools designed specifically to support patients treated with MOUD are limited.
methodsFollowing user-centered development and testing phases, a multi-feature smartphone application called HOPE (Heal. Overcome. Persist. Endure) was piloted in a small cohort of patients receiving MOUD and at high risk of disengagement in care at an office-based opioid treatment (OBOT) clinic in Central Virginia. Outcomes were tracked over a six-month period following patient enrollment. They included retention in care at the OBOT clinic, usage of various features of the application, and self-rated measures of mental health, substance use, treatment and recovery.
resultsOf the 25 participants in the HOPE pilot study, a majority were retained in care at 6 months (56%). Uptake of bi-directional features including messaging with providers and daily check-ins of mood, stress and medication adherence peaked at one month, and usage persisted through the sixth month. Patients who reported that distance to clinic was a problem at baseline had higher loss to follow up compared to those without distance as a reported barrier (67% vs 23%, p = 0.03). Patients lost to in-person clinic follow up continued to engage with one or more app features, indicating that mHealth approaches may bridge barriers to clinic visit attendance. Participants surveyed at baseline and 6 months (N = 16) scored higher on scales related to overall self-control and self-efficacy related to drug abstinence.
conclusionsA pilot study of a novel multi-feature smartphone application to support OUD treatment showed acceptable retention in care and patient usage at 6 months. Further study within a larger population is needed to characterize 'real world' uptake and association with outcomes related to retention in care, relapse prevention, and opioid-associated mortality.
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