Evidence map›Paper›PMID 35255949›Full record

Observational studyCritical care (London, England)2022

Limitations of the ARDS criteria during high-flow oxygen or non-invasive ventilation: evidence from critically ill COVID-19 patients.

Michael Hultström, Ola Hellkvist, Lucian Covaciu, Filip Fredén, Robert Frithiof, Miklós Lipcsey, Gaetano Perchiazzi, Mariangela Pellegrini

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Critical care (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Predictive modeling of ARDS mortality integrating biomarker/cytokine, clinical and metabolomic data.Translational research : the journal of laboratory and clinical medicine · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Michael HultströmAnaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Akademiska sjukhuset, ANOPIVA, Ing70, 2tr, 75185, Uppsala, Sweden. michael.hultstrom@mcb.uu.se.
Ola HellkvistAnaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Akademiska sjukhuset, ANOPIVA, Ing70, 2tr, 75185, Uppsala, Sweden.
Lucian CovaciuAnaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Akademiska sjukhuset, ANOPIVA, Ing70, 2tr, 75185, Uppsala, Sweden.
Filip FredénAnaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Akademiska sjukhuset, ANOPIVA, Ing70, 2tr, 75185, Uppsala, Sweden.
Robert FrithiofAnaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Akademiska sjukhuset, ANOPIVA, Ing70, 2tr, 75185, Uppsala, Sweden.
Miklós LipcseyAnaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Akademiska sjukhuset, ANOPIVA, Ing70, 2tr, 75185, Uppsala, Sweden.
Gaetano PerchiazziAnaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Akademiska sjukhuset, ANOPIVA, Ing70, 2tr, 75185, Uppsala, Sweden.
Mariangela PellegriniAnaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Akademiska sjukhuset, ANOPIVA, Ing70, 2tr, 75185, Uppsala, Sweden.
Uppsala University Hospital · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ratio of partial pressure of arterial oxygen to inspired oxygen fraction (PaO

methodsWe investigated respiratory function in critically ill patients with COVID-19 included in a single-center prospective observational study of patients admitted to the intensive care unit (ICU) at Uppsala University Hospital in Sweden. In a steady state condition, the PaO

resultsA total of 148 patients were included in the present analysis. We find that any change in respiratory support from or to HFNC caused a significant change in PaO

conclusionsHFNC is associated with lower PaO

Indexed as

COVID-19Noninvasive VentilationRespiratory Distress SyndromeRespiratory InsufficiencyCannulaCritical IllnessHumansOxygenOxygen Inhalation TherapyRespiration, ArtificialRNA, ViralSARS-CoV-2OxygenRNA, ViralAcute respiratory distress syndromeHigh-flow oxygenMechanical ventilationNon-invasive ventilation

Identifiers

PMID35255949
PMCPMC8899791
OpenAlexW4220851038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.