Evidence map›Paper›PMID 35255883›Full record

ArticleBMC biotechnology2022

Efficient extraction and antioxidant activity of polyphenols from Antrodia cinnamomea.

JianZhi Chu, YongFei Ming, Qi Cui, Na Zheng, ShuDe Yang, WeiHuan Li, Hongwei Gao, Rui Zhang, XianHao Cheng

Open access · goldAbstract read
In one paragraph

Article in BMC biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

JianZhi Chu *Shandong Key Lab of Edible Mushroom Technology, School of Agriculture, Ludong University, Yantai, 264025, China.
YongFei Ming *School of Life Science, Ludong University, Yantai, 264025, Shandong, China.
Qi CuiShandong Key Lab of Edible Mushroom Technology, School of Agriculture, Ludong University, Yantai, 264025, China.
Na ZhengShandong Key Lab of Edible Mushroom Technology, School of Agriculture, Ludong University, Yantai, 264025, China.
ShuDe YangShandong Key Lab of Edible Mushroom Technology, School of Agriculture, Ludong University, Yantai, 264025, China.
WeiHuan LiShandong Key Lab of Edible Mushroom Technology, School of Agriculture, Ludong University, Yantai, 264025, China.
Hongwei GaoSchool of Life Science, Ludong University, Yantai, 264025, Shandong, China.
Rui ZhangShandong Key Lab of Edible Mushroom Technology, School of Agriculture, Ludong University, Yantai, 264025, China. zhlrui@163.com.
XianHao ChengShandong Key Lab of Edible Mushroom Technology, School of Agriculture, Ludong University, Yantai, 264025, China. chengxianhao@sohu.com.
Ludong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntrodia cinnamomea, a rare medicinal fungus, has been increasingly studied in recent years because of its abundant secondary metabolites which are beneficial to humans. However, there is a lack of research on its polyphenols which are of good research value due to their antioxidant, anti-inflammatory, hypoglycemic and other activities.

resultsIn this study, the effects of different extraction conditions on the yield of its polyphenols were investigated. Deep-Eutectic Solvents composed of choline chloride and malonic acid had the best extraction efficiency, with the optimal extraction conditions being as follows: a solid-liquid ratio of 40 mg/mL, an extraction temperature of 55 °C, an extraction time of 70 min and a DES with 20% water content. Under these conditions, the extraction yield of polyphenols reached 22.09 mg/g which was about 2 times that of alcohol-based extraction (10.95 mg/g). In vitro antioxidant test results further showed that polyphenols from A. cinnamomea had strong antioxidant activities. When the concentration of polyphenols reached 0.1 mg/mL of polyphenols, the scavenging activity of free radical basically reached its maximum, with values of 94.10%, 83.34% and 95.42% for DPPH, ABTS

conclusionsThis study lays the foundation for the efficient extraction and application of polyphenols from A. cinnamomea.

Indexed as

AntioxidantsPolyphenolsHumansPlant ExtractsPolyporalesSolventsAntioxidantsPlant ExtractsPolyphenolsSolventsAntioxidantAntrodia cinnamomeaDeep eutectic solvents (DESs)ExtractionPolyphenols

Identifiers

PMID35255883
PMCPMC8903569
OpenAlexW4220659627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.