Evidence map›Paper›PMID 35255740›Full record

ArticleJournal of neurotrauma2022

Appendicular Fracture and Polytrauma Correlate with Outcome of Spinal Cord Injury: A Transforming Research and Clinical Knowledge in Spinal Cord Injury Study.

Theodore A Miclau, Abel Torres-Espin, Saam Morshed, Kazuhito Morioka, J Russell Huie, Ashraf N El Naga, Austin Chou, Lisa Pascual, Xuan Duong-Fernandez, Yu-Hung Kuo and 7 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurotrauma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Theodore A MiclauSchool of Medicine, Spine Center, University of California San Francisco, San Francisco, California, USA.
Abel Torres-EspinDepartment of Neurological Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Saam MorshedDepartment of Orthopaedic Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Kazuhito MoriokaDepartment of Neurological Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
J Russell HuieDepartment of Neurological Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Ashraf N El NagaDepartment of Orthopaedic Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Austin ChouDepartment of Neurological Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Lisa PascualBrain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, California, USA.
Xuan Duong-FernandezDepartment of Neurological Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Yu-Hung KuoDepartment of Neurological Surgery, UCSF-Fresno, Fresno, California, USA.
Philip WeinsteinDepartment of Neurological Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Sanjay S DhallDepartment of Neurological Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Jacqueline C BresnahanDepartment of Neurological Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Michael S BeattieDepartment of Neurological Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Anthony DigiorgioDepartment of Neurological Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Adam R FergusonDepartment of Neurological Surgery, Spine Center, University of California San Francisco, San Francisco, California, USA.
Transforming Research and Clinical Knowledge in Spinal Cord Injury (TRACK-SCI) Investigators
San Francisco General Hospital · USUniversity of California, San Francisco · USCalifornia State University, Fresno · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal cord injuries (SCIs) frequently occur in combination with other major organ injuries, such as traumatic brain injury (TBI) and injuries to the chest, abdomen, and musculoskeletal system (e.g., extremity, pelvic, and spine fractures). However, the effects of appendicular fractures on SCI recovery are poorly understood. We investigated whether the presence of SCI-concurrent appendicular fractures is predictive of a less robust SCI recovery. Patients enrolled in the Transforming Research and Clinical Knowledge in SCI (TRACK-SCI) prospective cohort study were identified and included in this secondary analysis study. Inclusion criteria resulted in 147 patients, consisting of 120 with isolated SCIs and 27 with concomitant appendicular fracture. The primary outcome was American Spinal Injury Association (ASIA) Impairment Scale (AIS) neurological grades at hospital discharge. Secondary outcomes included hospital length of stay, intensive care unit (ICU) length of stay, and AIS grade improvement during hospitalization. Multivariable binomial logistical regression analyses assessed whether SCI-concomitant appendicular fractures associate with SCI function and secondary outcomes. These analyses were adjusted for age, gender, injury severity, and non-fracture polytrauma. Appendicular fractures were associated with more severe AIS grades at hospital discharge, though covariate adjustments diminished statistical significance of this effect. Notably, non-fracture injuries to the chest and abdomen were influential covariates. Secondary analyses suggested that appendicular fractures also increased hospital length of stay. Our study indicated that SCI-associated polytrauma is important for predicting SCI functional outcomes. Further statistical evaluation is required to disentangle the effects of appendicular fractures, non-fracture solid organ injury, and SCI physiology to improve health outcomes among SCI patients.

Indexed as

Fractures, BoneMultiple TraumaSpinal Cord InjuriesSpinal FracturesHumansProspective StudiesRetrospective StudiesAISappendicular fractureslength of staypolytraumatic SCIrecoveryTRACK-SCI

Identifiers

PMID35255740
PMCPMC9536347
OpenAlexW4220868014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.