Evidence map›Paper›PMID 35255539›Full record

ArticleAllergy, asthma & immunology research2022

Real-world Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Newly Treated Korean Patients With Asthma: A Retrospective Cohort Study.

Nam-Kyong Choi, Sumitra Shantakumar, Mi-Sook Kim, Chang-Hoon Lee, Wendy Y Cheng, Priyanka Bobbili, Bo Ram Yang, Joongyub Lee, David Hinds, Mei Sheng Duh and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Nam-Kyong ChoiDepartment of Health Convergence, Ewha Womans University, Seoul, Korea.ORCID https://orcid.org/0000-0003-1153-9928
Sumitra ShantakumarEpidemiology and Health Economics, Greater China & Intercontinental Region, Medical Affairs, GlaxoSmithKline plc. Vaccines, Singapore.ORCID https://orcid.org/0000-0001-5814-6465
Mi-Sook KimDepartment of Preventive Medicine, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0002-4505-9167
Chang-Hoon LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-9960-1524
Wendy Y ChengAnalysis Group Inc., Boston, MA, USA.ORCID https://orcid.org/0000-0002-8281-2496
Priyanka BobbiliAnalysis Group Inc., Boston, MA, USA.ORCID https://orcid.org/0000-0002-1343-8314
Bo Ram YangMedical Research Collaborating Center, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-8771-8829
Joongyub LeeDepartment of Prevention and Management, Inha University Hospital, School of Medicine, Inha University, Incheon, Korea.ORCID https://orcid.org/0000-0003-2784-3772
David HindsReal World Evidence and Epidemiology, GlaxoSmithKline plc., Collegeville, PA, USA.ORCID https://orcid.org/0000-0003-0219-9941
Mei Sheng DuhAnalysis Group Inc., Boston, MA, USA.ORCID https://orcid.org/0000-0001-5035-6687
Caroline KorvesAnalysis Group Inc., Boston, MA, USA.ORCID https://orcid.org/0000-0001-8598-5176
Heung-Woo ParkDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. guinea71@snu.ac.kr.ORCID https://orcid.org/0000-0002-6970-3228
Analysis Group (United States) · USSeoul National University · KRSeoul National University Hospital · KREwha Womans University · KRGlaxoSmithKline (China) · CNGlaxoSmithKline (United States) · USInha University Hospital · KR

Funding

GlaxoSmithKline 208971
6 · The paper itself

Abstract

purposeAlthough asthma treatment guidelines recommend regular inhaled medication, real-world treatment patterns and outcomes in South Korea have not been examined. We examined real-world treatment patterns and outcomes among patients treated for asthma in South Korea.

methodsThis retrospective cohort study utilized data from the South Korean National Health Insurance database (2013-2016). Newly treated patients with asthma aged ≥18 years without history of chronic obstructive pulmonary disease were included. Initial and maintenance medication prescriptions were examined. Treatment discontinuation and switch were described. Asthma exacerbation rates, poor asthma control, and healthcare resource utilization (HRU) were compared between maintenance treatment groups (inhaled versus oral) using adjusted incidence rate ratios (aIRR) and hazard ratios (aHR).

resultsOverall, 1,054,707 patients initiated any asthma medication; 37,868 patients initiated inhaled (n = 9,983, 26.4%) or oral (n = 27,885, 73.6%) maintenance medication. More patients initiating inhaled versus oral asthma medication discontinued treatment within 12 months (94.4% vs. 86.3%;

conclusionsDespite current asthma guidelines, more patients in South Korea were prescribed oral than inhaled medications, resulting in suboptimal asthma management and increased HRU. This study highlights the need to reduce oral corticosteroid prescriptions for optimized treatment in asthma management.

Indexed as

Asthmaclinical guidelineshealth resourceinhalation devicesKoreapharmacologyprimary care

Identifiers

PMID35255539
PMCPMC8914610
OpenAlexW4214837398

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.