SynthesisHamostaseologie2022
Cardiac and Cerebral Arterial Complications of Lemierre Syndrome: Results from a Systematic Review and Individual Patient Data Meta-analysis.
Synthesis in Hamostaseologie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- An atypical presentation of Lemierre syndrome in a child with nephrotic syndrome: a case report and literature review.International journal of emergency medicine · 2026Article
- Central nervous system complications: atypical manifestation of Lemierre syndrome.BMC neurology · 2026Article
- Article
- Article
- A Case Report of Spontaneous Coronary Artery Dissection in Pregnancy: A Challenging Diagnosis.Cureus · 2025Article
- Review
- Lemierre Syndrome Associated withInfectious disease reports · 2024Article
- Article
- Lemierre's syndrome presenting with arterial and Central nervous system involvement.BJR case reports · 2024Article
- Case Report on Mycobacterium tuberculosis Presenting As Lemierre's Syndrome: A Reemerging Catastrophe.Cureus · 2024Article
- Hybrid approach to management for a patient with culture negative infective endocarditis with profunda femoris mycotic pseudoaneurysm: A case report and review of the literature.Clinical case reports · 2024Article
- Article
- Complex Lemierre syndrome with multisystemic abscesses.BMJ case reports · 2023Article
- Lemierre's Syndrome Complicated by Common Carotid Artery Pseudoaneurysm with Sentinel Bleed - A Case Report.Annals of maxillofacial surgeryArticle
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLemierre syndrome is a potentially life-threatening disease, which affects otherwise healthy young adults and adolescents. It is characterized by acute neck vein thrombosis and septic embolism, usually complicating a bacterial infection. Data on the syndrome are sparse, particularly concerning arterial complications.
methodsWe evaluated the frequency and patterns of cerebral arterial and cardiac involvement ("arterial complications") in an individual patient level cohort of 712 patients, representing all cases described over the past 20 years in the medical literature who fulfilled the criteria: (1) bacterial infection in the neck/head site and (2) objectively confirmed thrombotic complication or septic embolism. The study outcomes were defined as all-cause in-hospital deaths and the occurrence of clinical sequelae at discharge or in the postdischarge period.
resultsA total of 55 (7.7%) patients had an arterial complication. The most frequent arterial complications were carotid involvement (52.7%), stroke (38.2%), and pericardial complications (20%). Patients with an arterial involvement were more likely to be treated with a greater number of antibiotics (23 vs. 10%) and to receive anticoagulation. In addition, patients with arterial complications had a greater risk of all-cause death (
conclusionsWhile Lemierre syndrome is known to be primarily characterized by venous thromboembolic events, our results suggest that local or distant arterial complications may occur in approximately one-tenth of patients and may be associated with a greater risk of long-term sequelae and death.
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