Evidence map›Paper›PMID 35254909›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

KARRIKIN UP-REGULATED F-BOX 1 (KUF1) imposes negative feedback regulation of karrikin and KAI2 ligand metabolism in

Claudia Sepulveda, Michael A Guzmán, Qingtian Li, José Antonio Villaécija-Aguilar, Stephanie E Martinez, Muhammad Kamran, Aashima Khosla, Wei Liu, Joshua M Gendron, Caroline Gutjahr and 2 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Negative feedback regulation of karrikin signaling inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Review
  4. Article
  5. Genome-Wide Identification and Characterization of theInternational journal of molecular sciences · 2026
    Article
  6. Molecular insights into volatile organic compound sensing and signaling in plants.The Plant journal : for cell and molecular biology · 2026
    Review
  7. Review
  8. An N-terminal domain specifies developmental control by the SMAX1-LIKE family of transcriptional regulators inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. The Multifaceted Impact of Karrikin Signaling in Plants.International journal of molecular sciences · 2025
    Review
  10. Structural requirements of KAI2 ligands for activation of signal transduction.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Evolution of small molecule-mediated regulation of arbuscular mycorrhiza symbiosis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Chromosome-level genome assembly ofFrontiers in plant science · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Claudia SepulvedaDepartment of Botany and Plant Sciences, University of California, Riverside, CA 92521.ORCID 0000-0001-6044-9852
Michael A GuzmánDepartment of Botany and Plant Sciences, University of California, Riverside, CA 92521.ORCID 0000-0002-8047-5449
Qingtian LiDepartment of Botany and Plant Sciences, University of California, Riverside, CA 92521.
José Antonio Villaécija-AguilarPlant Genetics, TUM School of Life Sciences, Technical University of Munich, Freising, 85354 Germany.ORCID 0000-0001-6378-105X
Stephanie E MartinezDepartment of Botany and Plant Sciences, University of California, Riverside, CA 92521.ORCID 0000-0002-7008-5164
Muhammad KamranSchool of Molecular Sciences, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0003-4511-7766
Aashima KhoslaDepartment of Botany and Plant Sciences, University of California, Riverside, CA 92521.ORCID 0000-0001-8533-4269
Wei LiuDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511.ORCID 0000-0002-5693-4086
Joshua M GendronDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511.ORCID 0000-0001-8605-3047
Caroline GutjahrPlant Genetics, TUM School of Life Sciences, Technical University of Munich, Freising, 85354 Germany.ORCID 0000-0001-6163-745X
Mark T WatersSchool of Molecular Sciences, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0001-5657-9005
David C NelsonDepartment of Botany and Plant Sciences, University of California, Riverside, CA 92521.ORCID 0000-0001-9792-5015
University of California, Riverside · USTechnical University of Munich · DEThe University of Western Australia · AUYale University · US

Funding

Protein degradation mechanisms that regulate daily and seasonal timingR35GM128670 · NIGMS · YALE UNIVERSITY · PI Joshua Martin Gendron · 2018 to 2026
$4.0M
NIGMS NIH HHS R35 GM128670
6 · The paper itself

Abstract

SignificanceKarrikins are chemicals in smoke that stimulate regrowth of many plants after fire. However, karrikin responses are not limited to species from fire-prone environments and can affect growth after germination. Putatively, this is because karrikins mimic an unknown signal in plants, KAI2 ligand (KL). Karrikins likely require modification in plants to become bioactive. We identify a gene,

Indexed as

Genes, PlantArabidopsisArabidopsis ProteinsFuransGene Expression Regulation, PlantHydrolasesPyransSeedlingsSignal Transduction3-methyl-2H-furo(2,3-c)pyran-2-oneArabidopsis ProteinsFuransHTL protein, ArabidopsisHydrolasesPyransbiosynthesisphotomorphogenesisplant hormonesproteolysissignaling

Identifiers

PMID35254909
PMCPMC8931227
OpenAlexW4221085011

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.