Evidence map›Paper›PMID 35254893›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

FliL ring enhances the function of periplasmic flagella.

Shuaiqi Guo, Hui Xu, Yunjie Chang, Md A Motaleb, Jun Liu

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. FlgY, PflA, and PflB form a spoke-ring network in the high-torque flagellar motor ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Review
  7. Tetrameric PilZ protein stabilizes stator ring in complex flagellar motor and is required for motility inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Molecular model of a bacterial flagellar motorbioRxiv : the preprint server for biology · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. The big chill: Growth ofQRB discovery · 2024
    Review
  17. Article
  18. Article
  19. Flagellar motor remodeling during swarming requires FliL.bioRxiv : the preprint server for biology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shuaiqi GuoDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536.
Hui XuDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834.
Yunjie ChangDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536.
Md A MotalebDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834.ORCID 0000-0003-2761-5104
Jun LiuDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536.ORCID 0000-0003-3108-6735
Yale University · USEast Carolina University · US

Funding

Structure-Function Relationships in the Spirochetal Flagellar MotorR01AI087946 · NIAID · YALE UNIVERSITY · PI LIU, JUN · 2010 to 2025
$6.6M
Delineation of unique flagellar proteins in spirochetesR01AI132818 · NIAID · EAST CAROLINA UNIVERSITY · PI Jun Liu, MD A MOTALEB · 2018 to 2026
$3.3M
High-throughput electron cryo-microscopeS10OD023603 · OD · YALE UNIVERSITY · PI SIGWORTH, FREDERICK J · 2018 to 2018
$1.9M
NIAID NIH HHS R01 AI087946NIAID NIH HHS R01 AI132818NIH HHS S10 OD023603
6 · The paper itself

Abstract

SignificanceHow flagella sense complex environments and control bacterial motility remain fascinating questions. Here, we deploy cryo-electron tomography to determine in situ structures of the flagellar motor in wild-type and mutant cells of

Indexed as

Bacterial Physiological PhenomenaBacterial ProteinsBorrelia burgdorferiFlagellaGene Expression Regulation, BacterialMembrane ProteinsModels, BiologicalModels, MolecularMolecular Motor ProteinsPeriplasmBacterial ProteinsFliL protein, BacteriaMembrane ProteinsMolecular Motor Proteinselectron tomographymechanosensormolecular machinemotilityspirochete

Identifiers

PMID35254893
PMCPMC8931381
OpenAlexW4220902280

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.