Evidence map›Paper›PMID 35254634›Full record

ArticleDermatology and therapy2022

Demographic and Clinical Factors Associated with Patient-Reported Remission in Psoriasis.

George Gondo, Edward Hadeler, Nicholas Brownstone, Emanual Maverakis, Joseph F Merola, April W Armstrong, Tina Bhutani, Stacie J Bell, Wilson Liao

Open access · goldAbstract read
In one paragraph

Article in Dermatology and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

George GondoNational Psoriasis Foundation, Portland, OR, USA.
Edward HadelerUniversity of California at San Francisco, San Francisco, CA, USA.
Nicholas BrownstoneUniversity of California at San Francisco, San Francisco, CA, USA.
Emanual MaverakisUniversity of California at Davis, Sacramento, CA, USA.
Joseph F MerolaBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
April W ArmstrongUniversity of Southern California, Los Angeles, CA, USA.
Tina BhutaniUniversity of California at San Francisco, San Francisco, CA, USA.
Stacie J BellOpsis Health/Global Nutrition Project, Colorado, USA.
Wilson LiaoUniversity of California at San Francisco, San Francisco, CA, USA. wilson.liao@ucsf.edu.ORCID http://orcid.org/0000-0001-7883-6439
Brigham and Women's Hospital · USNational Psoriasis Foundation · USUniversity of California, Davis · USUniversity of California, San Francisco · USUniversity of Southern California · US

Funding

Mentoring Translational Scientists in Clinical Trial Immune MonitoringK24AR077313 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MAVERAKIS, EMANUAL M. · 2021 to 2025
$939k
NIAMS NIH HHS K24 AR077313
6 · The paper itself

Abstract

introductionAchievement of remission in psoriasis is a key goal for patients and providers, yet definitions of remission may vary. Some treat-to-target initiatives in psoriasis have focused on degree of skin involvement, while others have also incorporated quality of life (QoL) measures. The goal of this study is to identify factors associated with patient-reported psoriasis remission.

methodsThe National Psoriasis Foundation conducted a survey of a random stratified sample of 1570 individuals with psoriatic disease in the USA. The survey contained questions regarding provider diagnosis of psoriasis and/or psoriatic arthritis, as well as comorbid conditions and participant demographics. Psoriasis severity was assessed using the Patient Report of Extent of Psoriasis Involvement (PREPI), a validated self-reported measure of body surface area (BSA). Dermatologic-related quality of life was assessed using the Dermatology Life Quality Index (DLQI). Individuals reporting BSA ≤ 3% were asked if they believed their psoriasis was in remission. Multivariate logistic regression was used to identify factors associated with remission.

resultsOf 930 participants reporting BSA ≤ 3%, 479 (51.7%) believed their psoriasis was in remission, with an average remission duration of 31 months. Of those in remission, 79.1% reported current treatment. Multivariate regression revealed that psoriasis remission was independently associated with female sex, lower BSA, less impairment in the Dermatology Life Quality Index and global QoL, biologic use, and concomitant diagnosis of psoriatic arthritis. There was no association with age, race, body mass index, or number of comorbidities.

conclusionOverall, patient perception of psoriasis remission was not solely associated with BSA, but also with sex, quality of life, and treatment type.

Indexed as

PsoriasisPsoriatic arthritisQuality of lifeRemissionTreat-to-target

Identifiers

PMID35254634
PMCPMC8941001
OpenAlexW4220950817

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.