Evidence map›Paper›PMID 35254602›Full record

ArticleGlycoconjugate journal2022

Protective Effects of a synthetic glycosaminoglycan mimetic (OTR4132) in a rat immunotoxic lesion model of septohippocampal cholinergic degeneration.

Patricia Marques Pereira, Dulce Papy-Garcia, Denis Barritault, Franck Chiappini, Rolf Jackisch, Sarah Schimchowitsch, Jean-Christophe Cassel

Open access · hybridAbstract read
In one paragraph

Article in Glycoconjugate journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Patricia Marques PereiraUMR 7364 LNCA, Université de Strasbourg, 12 rue Goethe, F-67000, Strasbourg, France.
Dulce Papy-GarciaGlycobiology, cell growth and tissue repair research unit (Gly- CRRET), Univ Paris Est Créteil (UPEC), F-94010, Créteil, France.ORCID 0000-0003-2225-9331
Denis BarritaultOrgan, Tissue, Regeneration, Repair and Replacement, OTR3 (SAS), 4 rue Française, F-75001, Paris, France.ORCID 0000-0003-0315-7444
Franck ChiappiniOrgan, Tissue, Regeneration, Repair and Replacement, OTR3 (SAS), 4 rue Française, F-75001, Paris, France. franck.chiappini@otr3.com.ORCID 0000-0002-2684-1241
Rolf JackischInstitute of Experimental and Clinical Pharmacology and Toxicology, Laboratory of Neuropharmacology, University of Freiburg, Hansastraße 9A, D-79104, Freiburg, Germany.
Sarah SchimchowitschUMR 7364 LNCA, Université de Strasbourg, 12 rue Goethe, F-67000, Strasbourg, France.ORCID 0000-0002-2838-4523
Jean-Christophe CasselUMR 7364 LNCA, Université de Strasbourg, 12 rue Goethe, F-67000, Strasbourg, France.ORCID 0000-0002-4490-9086
Université de Strasbourg · FRCentre National de la Recherche Scientifique · FRÉtablissement Français du Sang · FRUniversité Paris-Est Créteil · FRUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using a partial hippocampal cholinergic denervation model, we assessed the effects of the RGTA

Indexed as

AcetylcholinesteraseGlycosaminoglycansAnimalsCholinergic AgentsMaleRatsRats, Long-EvansRibosome Inactivating Proteins, Type 1AcetylcholinesteraseCholinergic AgentsGlycosaminoglycansRibosome Inactivating Proteins, Type 1AlzheimerHeparan sulfate mimeticHippocampusNeuroprotectionOTR4132Septohippocampal pathway

Identifiers

PMID35254602
PMCPMC8979900
OpenAlexW4220815407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.