Evidence map›Paper›PMID 35254247›Full record

ArticleJournal of studies on alcohol and drugs2022

Family-Based Predictors of Alcohol Use Disorder (AUD) Recurrence and New Non-Alcohol Substance Use Disorder Onset Following Initial AUD Recovery.

Richard F Farmer, Jeff M Gau, John R Seeley, Derek B Kosty

Open access · greenAbstract read
In one paragraph

Article in Journal of studies on alcohol and drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Richard F FarmerOregon Research Institute, Eugene, Oregon.
Jeff M GauOregon Research Institute, Eugene, Oregon.
John R SeeleyOregon Research Institute, Eugene, Oregon.
Derek B KostyOregon Research Institute, Eugene, Oregon.
Oregon Research Institute · USOregon Department of Education · USUniversity of Oregon · US

Funding

Risk for Substance Use Disorders and Comorbid ConditionsR01DA012951 · NIDA · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 2000 to 2004
$3.3M
Factors Associated with the Course and Outcomes of Alcohol Use Disorders in a Cohort Sample of Adolescents Followed into Early AdulthoodR01AA027543 · NIAAA · OREGON RESEARCH INSTITUTE · PI FARMER, RICHARD FRANCIS, SEELEY, JOHN R · 2019 to 2019
$239k
NATURAL HISTORY OF DEPRESSION IN ADOLESCENTSR01MH050522 · NIMH · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 1993 to 2001
$121k
ADOLESCENT DEPRESSION: PREVALENCE &PSYCHOSOCIAL ASPECTSR01MH040501 · NIMH · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 1986 to 1990
–
NIAAA NIH HHS R01 AA027543NIDA NIH HHS R01 DA012951NIMH NIH HHS R01 MH040501NIMH NIH HHS R01 MH050522
6 · The paper itself

Abstract

objectiveKnowledge of factors that predict alcohol use disorder (AUD) recurrence or the subsequent switching to a different substance use disorder (SUD) after initial AUD recovery is especially crucial for preventive efforts that seek to alter life courses dominated by problematic substance use. This study evaluated whether the proportions (or densities) of first-degree relatives with AUD and non-alcohol substance use disorder (NASUD) histories predicted AUD recurrence or a new NASUD onset in a family member (i.e., proband) following initial AUD episode recovery.

methodThis research is based on a prospective and multigenerational data set collected as part of the Oregon Adolescent Depression Project (OADP). The initial proband cohort was selected randomly from nine high schools in western Oregon. The sample for this research consisted of OADP probands with histories of AUD who recovered from their first AUD episode by age 30 (

resultsIn unadjusted and partially adjusted analyses, family densities of AUD predicted AUD recurrence among probands, and family densities of NASUDs predicted the onset of a new NASUD following first-episode AUD recovery. In fully adjusted analyses, the effect for AUD family histories on proband AUD recurrence remained, whereas the effect for family NASUD histories on new NASUD emergence was not maintained.

conclusionsFamily SUD histories have predictive relevance for the course of AUD following initial recovery as well as some specificity for the type of SUD recurrence subsequently experienced.

Indexed as

AlcoholismSubstance-Related DisordersAdolescentAdultAlcohol DrinkingFamilyHumansProspective Studies

Identifiers

PMID35254247
PMCPMC8909923
OpenAlexW4221081680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.