Evidence map›Paper›PMID 35254101›Full record

ArticleJournal of clinical microbiology2022

Prevalence and Mortality Associated with Bloodstream Organisms: a Population-Wide Retrospective Cohort Study.

Mark Verway, Kevin A Brown, Alex Marchand-Austin, Christina Diong, Samantha Lee, Bradley Langford, Kevin L Schwartz, Derek R MacFadden, Samir N Patel, Beate Sander and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 2 pooled it
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 2 syntheses or guidelines pooled it, 129 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Prognostic value of the identified genus of anaerobic bacteria in bloodstream infection beyond host-related risk factors: a five-year retrospective cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  6. Article
  7. Article
  8. Daptomycin and linezolid salvage therapy for persistent ampicillin-susceptibleJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2026
    Article
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  11. Article
  12. Review
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  14. Article
  15. Infection and immunity · 2026
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  19. Article
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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Mark VerwayUniversity of Toronto, Toronto, Canada.
Kevin A BrownUniversity of Toronto, Toronto, Canada.ORCID 0000-0002-1483-2188
Alex Marchand-AustinPublic Health Ontariogrid.415400.4, Toronto, Canada.
Christina DiongICES, Toronto, Canada.
Samantha LeeICES, Toronto, Canada.
Bradley LangfordPublic Health Ontariogrid.415400.4, Toronto, Canada.
Kevin L SchwartzPublic Health Ontariogrid.415400.4, Toronto, Canada.ORCID 0000-0002-3666-7005
Derek R MacFaddenThe Ottawa Hospital Research Institute, Ottawa, Canada.
Samir N PatelUniversity of Toronto, Toronto, Canada.
Beate SanderUniversity of Toronto, Toronto, Canada.
Jennie JohnstoneUniversity of Toronto, Toronto, Canada.
Gary GarberUniversity of Toronto, Toronto, Canada.
Nick DanemanUniversity of Toronto, Toronto, Canada.
University of Toronto · CAInstitute for Clinical Evaluative Sciences · CAPublic Health Ontario · CAOttawa Hospital · CASunnybrook Health Science Centre · CAUniversity Health Network · CA

Funding

Gouvernement du Canada | Canadian Institutes of Health Research (IRSC) 159503
6 · The paper itself

Abstract

Bloodstream infections (BSIs) represent a substantial mortality risk, yet most studies are limited to select pathogens or populations. The aim of this study was to describe the population-wide prevalence of BSIs and examine the associated mortality risk for the responsible microorganisms. We conducted a population-wide retrospective cohort study of BSIs in Ontario in 2017. Blood culture data was collected from almost all microbiology laboratories in Ontario and linked to data sets of patient characteristics. For each organism, we determined the prevalence and crude mortality risk, and using logistic regression models, the adjusted odds of 30-day mortality was calculated relative to patients with negative blood cultures and matched patients without blood culture testing. From 531,065 blood cultures, we identified 22,935 positive BSI episodes in 19,326 patients, for an incidence of 150 per 100,000 population. The most frequently isolated organisms were Escherichia coli, Staphylococcus aureus, coagulase-negative staphylococci,

Indexed as

BacteremiaCross InfectionSepsisStaphylococcal InfectionsEscherichia coliHumansPrevalenceRetrospective StudiesStaphylococcus aureusbacteremiabloodstream infectionpopulationsurveillance

Identifiers

PMID35254101
PMCPMC9020345
OpenAlexW4221014762

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.