Evidence map›Paper›PMID 35254089›Full record

ArticleAntimicrobial agents and chemotherapy2022

Characterization of Clofazimine as a Potential Substrate of Drug Transporter.

M Rasheduzzaman Jony, Yong-Soon Cho, Nguyen Phuoc Long, Ho-Jung Shin, Jae-Gook Shin

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. HBV/HCV coinfection and anti-tuberculosis drug-induced liver injury: from risk assessment and exploration of mechanisms to preventive considerations.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M Rasheduzzaman JonyCenter for Personalized Precision Medicine of Tuberculosis, Inje University College of Medicine, Busan, Republic of Korea.ORCID 0000-0001-5656-9085
Yong-Soon ChoCenter for Personalized Precision Medicine of Tuberculosis, Inje University College of Medicine, Busan, Republic of Korea.ORCID 0000-0003-1424-1123
Nguyen Phuoc LongCenter for Personalized Precision Medicine of Tuberculosis, Inje University College of Medicine, Busan, Republic of Korea.
Ho-Jung ShinDepartment of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Busan, Republic of Korea.
Jae-Gook ShinCenter for Personalized Precision Medicine of Tuberculosis, Inje University College of Medicine, Busan, Republic of Korea.
Inje University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we explored clofazimine (CFZ) as a potential substrate of uptake and efflux transporters that might be involved in CFZ disposition, using transporter gene overexpressing cell lines

Indexed as

ClofazimineNeoplasm ProteinsATP Binding Cassette Transporter, Subfamily G, Member 2Drug InteractionsHEK293 CellsHumansMembrane Transport ProteinsATP Binding Cassette Transporter, Subfamily G, Member 2ClofazimineMembrane Transport ProteinsNeoplasm Proteinsantituberculosisclofaziminemembrane transportersubstrate characterization

Identifiers

PMID35254089
PMCPMC9017350
OpenAlexW4220671781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.