Evidence map›Paper›PMID 35253919›Full record

ReviewMagnetic resonance in medicine2022

Hyperpolarized

Yurii Shepelytskyi, Vira Grynko, Madhwesha R Rao, Tao Li, Martina Agostino, Jim M Wild, Mitchell S Albert

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02638519 (Hyperpolarized Xenon-129 Functional Magnetic Resonance Imaging of Healthy Volunteers and Participants With Alzheimer's Disease), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02638519 early_phase1terminatednot on this map

Hyperpolarized Xenon-129 Functional Magnetic Resonance Imaging of Healthy Volunteers and Participants With Alzheimer's Disease

TypeinterventionalSponsorThunder Bay Regional Health Research InstituteRan2016 to 2022Enrolled51ConditionsAlzheimer DiseaseArmsTraditional Proton fMRI, Hyperpolarized Xenon-129 fMRI, Hyperpolarized Xenon-129, 1H-129Xe Dual-Tuned Quadrature Head Coil
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Relationship between Pulmonary Gas Exchange Function and Brain Uptake Dynamics Investigated with HyperpolarizedMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. HyperpolarizedMagnetic resonance in medicine · 2022
    Review
  9. Advances in Collateral Neuroimaging for Acute Ischemic Stroke: Redefining Time and Tissue Windows in the Reperfusion Era.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Yurii ShepelytskyiChemistry Department, Lakehead University, Thunder Bay, Ontario, Canada.ORCID 0000-0001-5526-7958
Vira GrynkoThunder Bay Regional Health Research Institute, Thunder Bay, Ontario, Canada.ORCID 0000-0002-9580-0072
Madhwesha R RaoPOLARIS, Unit of Academic Radiology, Department of IICD, University of Sheffield, Sheffield, UK.ORCID 0000-0002-4109-4176
Tao LiChemistry Department, Lakehead University, Thunder Bay, Ontario, Canada.
Martina AgostinoChemistry Department, Lakehead University, Thunder Bay, Ontario, Canada.
Jim M WildPOLARIS, Unit of Academic Radiology, Department of IICD, University of Sheffield, Sheffield, UK.
Mitchell S AlbertChemistry Department, Lakehead University, Thunder Bay, Ontario, Canada.
Thunder Bay Regional Research Institute · CALakehead University · CAInsigneo · GBUniversity of Sheffield · GB

Funding

British Heart Foundation SP/14/6/31350Medical Research Council MR/M008894/1
6 · The paper itself

Abstract

Hyperpolarized (HP) xenon-129 (

Indexed as

LungXenon IsotopesAnimalsBrainHumansMagnetic Resonance ImagingNeuroimagingXenon IsotopesbrainHP 129Xe brain imaginghyperpolarized xenon-129magnetic resonance imaging/spectroscopyperfusion imaging

Identifiers

PMID35253919
PMCPMC9314594
OpenAlexW4220823570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.