Evidence map›Paper›PMID 35253610›Full record

ArticleEmerging microbes & infections2022

Characterization and distribution of HIV-infected cells in semen.

Lin Gao, Yan-Mei Jiao, Ping Ma, Lijun Sun, Hongxin Zhao, An-Liang Guo, Xing Fan, Chao Zhang, Jin-Wen Song, Ji-Yuan Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Lin GaoDepartment of Microbiology & Infectious Disease Center, School of Basic Medical Science, Peking University Health Science Center, Beijing, People's Republic of China.
Yan-Mei JiaoSenior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, People's Republic of China.
Ping MaNankai University Second People's Hospital, School of Medicine, Nankai University, Tianjin, People's Republic of China.
Lijun SunCenter for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing, People's Republic of China.
Hongxin ZhaoClinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
An-Liang GuoDepartment of Microbiology & Infectious Disease Center, School of Basic Medical Science, Peking University Health Science Center, Beijing, People's Republic of China.
Xing FanSenior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, People's Republic of China.
Chao ZhangSenior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, People's Republic of China.
Jin-Wen SongSenior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, People's Republic of China.ORCID 0000-0002-8582-8012
Ji-Yuan ZhangSenior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, People's Republic of China.
Fengmin LuDepartment of Microbiology & Infectious Disease Center, School of Basic Medical Science, Peking University Health Science Center, Beijing, People's Republic of China.ORCID 0000-0002-1832-3209
Fu-Sheng WangDepartment of Microbiology & Infectious Disease Center, School of Basic Medical Science, Peking University Health Science Center, Beijing, People's Republic of China.
Chinese PLA General Hospital · CNCapital Medical University · CNPeking University · CNShandong University · CNNankai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Semen is a known vector for both human immunodeficiency virus (HIV) infection and transmission. However, the distribution and characteristics of HIV-infected cells in semen remain unclear. Investigating the possibility of transmission through the spermatozoon in semen is of great clinical significance to improve the strategies for exposure prevention and assisted reproduction for HIV-infected partners. Twenty-six HIV-infected patients, including twelve treatment-naïve (TN) patients and fourteen antiretroviral treated (ART) patients, were enrolled in this study. HIV p24 protein in spermatozoa was detected using imaging flow cytometry and immunohistochemistry, and HIV RNA was identified using next-generation RNAscope

Indexed as

HIV InfectionsLeukocytes, MononuclearHIV Core Protein p24HumansMaleSpermatozoaHIV Core Protein p24CC chemokine receptor 5CD4+ T cellCXC chemokine receptor 4HIVspermatozoa

Identifiers

PMID35253610
PMCPMC8942556
OpenAlexW4220908523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.