Evidence map›Paper›PMID 35253449›Full record

ArticleJournal of the American Heart Association2022

Ankle-Brachial Index and Energy Production in People Without Peripheral Artery Disease: The BLSA.

Matt T Oberdier, Majd AlGhatrif, Fatemeh Adelnia, Marta Zampino, Christopher H Morrell, Eleanor Simonsick, Kenneth Fishbein, Edward G Lakatta, Mary M McDermott, Luigi Ferrucci

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matt T OberdierLaboratory of Cardiovascular Science National Institute on Aging Baltimore MD.
Majd AlGhatrifLaboratory of Cardiovascular Science National Institute on Aging Baltimore MD.ORCID 0000-0002-7642-2643
Fatemeh AdelniaLongitudinal Studies Section National Institute on Aging Baltimore MD.
Marta ZampinoLongitudinal Studies Section National Institute on Aging Baltimore MD.
Christopher H MorrellLaboratory of Cardiovascular Science National Institute on Aging Baltimore MD.
Eleanor SimonsickLongitudinal Studies Section National Institute on Aging Baltimore MD.
Kenneth FishbeinLaboratory of Clinical Investigation National Institute on Aging Baltimore MD.
Edward G LakattaLaboratory of Cardiovascular Science National Institute on Aging Baltimore MD.
Mary M McDermottDepartment of Medicine Northwestern University Feinberg School of Medicine Chicago IL.ORCID 0000-0002-3724-7619
Luigi FerrucciLongitudinal Studies Section National Institute on Aging Baltimore MD.ORCID 0000-0002-6273-1613

Funding

The Baltimore Longitudinal Study Of AgingZIAAG000015 · NIA · NATIONAL INSTITUTE ON AGING · PI SIMONSICK, ELEANOR MARIE · 2009 to 2025
$116.9M
Changes in muscle biomechanical quality with aging: causes and consequencesZIAAG000995 · NIA · NATIONAL INSTITUTE ON AGING · PI FERRUCCI, LUIGI · 2015 to 2025
$875k
6 · The paper itself

Abstract

Background Lower ankle-brachial index (ABI) values within the 0.90 to 1.40 range are associated with poorer mitochondrial oxidative capacity of thigh muscles in cross-sectional analyses. Whether ABI decline is associated with greater declines in thigh muscle oxidative capacity with aging is unknown. Method and Results We analyzed data from 228 participants (100 men) of the BLSA (Baltimore Longitudinal Study of Aging), aged 39 to 97 years, with an ABI between 0.9 and 1.40 at baseline and at follow-up (mean follow-up period of 2.8 years). We examined mitochondrial oxidative capacity of the left thigh muscle, by measuring the postexercise phosphocreatine recovery rate constant (

Indexed as

AgingAnkle Brachial IndexAdultAgedAged, 80 and overFemaleHumansLongitudinal StudiesMaleMiddle AgedRisk Factorsagingepidemiologyperipheral vascular diseaseprimary prevention

Identifiers

PMID35253449
PMCPMC9075330

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.