ArticleJournal of the American Heart Association2022
Cardiac Structure and Function and Diabetes-Related Risk of Death or Heart Failure in Older Adults.
Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Cumulative effect of hyperglycemia and insulin resistance on cardiac dysfunction: The coronary artery risk development in young adults (CARDIA) study.American heart journal · 2026Article
- Sociodemographic Factors, Physical Activity and Glycemic Control in Adults with Diabetes: A Pilot Study from a Croatian Reference Center.Nursing reports (Pavia, Italy) · 2025Article
- Small left ventricular size as a predictor for incident type 2 diabetes: insights from the UK biobank cardiovascular magnetic resonance substudy.Diabetology & metabolic syndrome · 2025Article
- Association between metabolic visceral fat score and left ventricular hypertrophy in individuals with type 2 diabetes.Diabetology & metabolic syndrome · 2025Article
- Review
- The impact of triglyceride glucose-body mass index on all-cause and cardiovascular mortality in elderly patients with diabetes mellitus: evidence from NHANES 2007-2016.BMC geriatrics · 2024Article
- Epigenetic modifier alpha-ketoglutarate modulates aberrant gene body methylation and hydroxymethylation marks in diabetic heart.Epigenetics & chromatin · 2023Article
- Reverse Atrial Remodeling in Heart Failure With Recovered Ejection Fraction.Journal of the American Heart Association · 2023Article
- Association Between Left Ventricular Strains and Cardiovascular Risk Factors in Type 2 Diabetic Patients: a Controlled Cross-sectional Study.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023Article
- Left atrial disease and left atrial reverse remodelling across different stages of heart failure development and progression: a new target for prevention and treatment.European journal of heart failure · 2022Review
- A Novel Composite Indicator of Predicting Mortality Risk for Heart Failure Patients With Diabetes Admitted to Intensive Care Unit Based on Machine Learning.Frontiers in endocrinology · 2022Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
Background Whether cardiac structure and function abnormalities associated with dysglycemia are sufficient to explain the increased risk of death or heart failure (HF) remains unclear. Methods and Results We analyzed 6059 participants (mean age, 75±5 years; 58% women; and 22% Black individuals) who attended the ARIC (Atherosclerosis Risk in Communities) study visit 5 examination (2011-2013). Participants were categorized as no diabetes, pre-diabetes, and diabetes (on the basis of medical history and glycated hemoglobin values). We assessed whether diabetes modified the association between echocardiographic measures of cardiac structure and function and the composite of all-cause death or HF hospitalization and then estimated the extent to which the increased risk of the composite outcome associated with diabetes was explained by cardiac structure and function. Diabetes was prevalent in 33.5% of the subjects. Death or HF occurred in 1111 (18%) at a rate of 3.6 per 100 person-years. Both measures of cardiac structure and function and diabetes status were significantly associated with worse prognosis after accounting for clinical confounders. While diabetes was consistently associated with a higher risk of events, it did not significantly modify the association between cardiac abnormalities and the risk of death or HF, except for subjects with higher left atrial volume who showed higher relative risk of events (
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