Evidence map›Paper›PMID 35253378›Full record

SynthesisClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2022

Artificial intelligence to classify ear disease from otoscopy: A systematic review and meta-analysis.

Al-Rahim Habib, Majid Kajbafzadeh, Zubair Hasan, Eugene Wong, Hasantha Gunasekera, Chris Perry, Raymond Sacks, Ashnil Kumar, Narinder Singh

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Artificial intelligence to classify ear disease from otoscopy: A systematic review and meta-analysis.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2022
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  11. High-definition otoscopic device for humanitarian mission: how i do it.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Al-Rahim HabibFaculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-6327-4648
Majid KajbafzadehFaculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
Zubair HasanDepartment of Otolaryngology - Head and Neck Surgery, Westmead Hospital, Westmead, New South Wales, Australia.
Eugene WongDepartment of Otolaryngology - Head and Neck Surgery, Westmead Hospital, Westmead, New South Wales, Australia.ORCID 0000-0002-5799-5083
Hasantha GunasekeraFaculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
Chris PerryDepartment of Otolaryngology - Head and Neck Surgery, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.
Raymond SacksFaculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
Ashnil KumarSchool of Biomedical Engineering, Faculty of Engineering, University of Sydney, Sydney, New South Wales, Australia.
Narinder SinghFaculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
The University of Sydney · AUWestmead Hospital · AUThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo summarise the accuracy of artificial intelligence (AI) computer vision algorithms to classify ear disease from otoscopy.

designSystematic review and meta-analysis.

methodsUsing the PRISMA guidelines, nine online databases were searched for articles that used AI computer vision algorithms developed from various methods (convolutional neural networks, artificial neural networks, support vector machines, decision trees and k-nearest neighbours) to classify otoscopic images. Diagnostic classes of interest: normal tympanic membrane, acute otitis media (AOM), otitis media with effusion (OME), chronic otitis media (COM) with or without perforation, cholesteatoma and canal obstruction.

main outcome measuresAccuracy to correctly classify otoscopic images compared to otolaryngologists (ground truth). The Quality Assessment of Diagnostic Accuracy Studies Version 2 tool was used to assess the quality of methodology and risk of bias.

resultsThirty-nine articles were included. Algorithms achieved 90.7% (95%CI: 90.1-91.3%) accuracy to difference between normal or abnormal otoscopy images in 14 studies. The most common multiclassification algorithm (3 or more diagnostic classes) achieved 97.6% (95%CI: 97.3-97.9%) accuracy to differentiate between normal, AOM and OME in three studies. AI algorithms outperformed human assessors to classify otoscopy images achieving 93.4% (95%CI: 90.5-96.4%) versus 73.2% (95%CI: 67.9-78.5%) accuracy in three studies. Convolutional neural networks achieved the highest accuracy compared to other classification methods.

conclusionAI can classify ear disease from otoscopy. A concerted effort is required to establish a comprehensive and reliable otoscopy database for algorithm training. An AI-supported otoscopy system may assist health care workers, trainees and primary care practitioners with less otology experience identify ear disease.

Indexed as

Ear DiseasesOtitis MediaOtitis Media with EffusionArtificial IntelligenceHumansOtoscopesOtoscopyartificial intelligencecomputer visiondiagnosismachine learningotoscopy

Identifiers

PMID35253378
PMCPMC9310803
OpenAlexW4220688195

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.