Evidence map›Paper›PMID 35253072›Full record

ArticleEuropean journal of nutrition2022

Association of dietary and plasma carotenoids with urinary F

Yong-Moon Mark Park, Jenna Lilyquist, Thomas J Van't Erve, Katie M O'Brien, Hazel B Nichols, Ginger L Milne, Clarice R Weinberg, Dale P Sandler

Open access · greenAbstract read
In one paragraph

Article in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Understanding mechanisms of antioxidant action in health and disease.Nature reviews. Molecular cell biology · 2024
    Review
  6. Article
  7. Carotenoids in Health as Studied by Omics-Related Endpoints.Advances in nutrition (Bethesda, Md.) · 2023
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Yong-Moon Mark ParkDepartment of Epidemiology, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, 4301 W. Markham St., #820, Little Rock, AR, 72205, USA. ypark@uams.edu.ORCID http://orcid.org/0000-0002-5879-6879
Jenna LilyquistSocial and Scientific Systems, Inc, Durham, NC, USA.
Thomas J Van't ErveEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Mail Drop A3-05 111 T.W. Alexander Drive, Research Triangle Park, NC, 27709, USA.
Katie M O'BrienEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Mail Drop A3-05 111 T.W. Alexander Drive, Research Triangle Park, NC, 27709, USA.
Hazel B NicholsDepartment of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.
Ginger L MilneDivision of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.
Clarice R WeinbergBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Dale P SandlerEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Mail Drop A3-05 111 T.W. Alexander Drive, Research Triangle Park, NC, 27709, USA. sandler@niehs.nih.gov.ORCID http://orcid.org/0000-0002-6776-0018
National Institutes of Health · USNational Institute of Environmental Health Sciences · USSocial and Scientific Systems (United States) · USUniversity of North Carolina at Chapel Hill · USVanderbilt University Medical Center · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
Environmental and Genetic Risk Factors For Breast Cancer: The Sister StudyZIAES044005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 2009 to 2025
$22.7M
The Two Sister StudyZIAES102245 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WEINBERG, CLARICE · 2009 to 2025
$8.6M
Genetic and Environmental Risk Factors for Breast Cancer: The Sister StudyZ01ES044005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 1999 to 2008
$1.3M
Intramural NIH HHS Z01 ES044005NIEHS NIH HHS P30 ES010126NIEHS NIH HHS Z01-ES044005NIH HHS NIH Office of Dietary Supplements Research Scholars Program
6 · The paper itself

Abstract

purposeCarotenoids may protect against chronic diseases including cancer and cardiometabolic disease by mitigating oxidative stress and/or inflammation. We cross-sectionally evaluated associations between carotenoids and biomarkers of oxidative stress or inflammation.

methodsFrom 2003 to 2009, the Sister Study enrolled 50,884 breast cancer-free US women aged 35-74. Post-menopausal participants (n = 512) were randomly sampled to measure carotenoids and biomarkers of oxidative stress. Dietary carotenoid consumption was assessed using a validated 110-item Block 1998 food frequency questionnaire; use of β-carotene-containing supplements was also assessed. Plasma carotenoids were quantified, adjusting for batch. Urinary markers of lipid peroxidation, 8-iso-prostaglandin F

resultsTotal plasma carotenoids were inversely associated with 8-iso-PGF

conclusionPlasma carotenoids and supplemental β-carotene were associated with lower concentrations of 8-iso-PGF

Indexed as

F2-IsoprostanesIsoprostanesbeta CaroteneBiomarkersCarotenoidsDinoprostFemaleHumansInflammationLuteinOxidative StressZeaxanthinsbeta CaroteneBiomarkersCarotenoidsDinoprostF2-IsoprostanesIsoprostanesLuteinZeaxanthinsCarotenoidsF2-isoprostanesInflammationOxidative stress

Identifiers

PMID35253072
PMCPMC9283284
OpenAlexW4220859163

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.