Evidence map›Paper›PMID 35253001›Full record

ArticleJACS Au2022

Calcium Contributes to Polarized Targeting of HIV Assembly Machinery by Regulating Complex Stability.

Chandan Kishor, Belinda L Spillings, Johana Luhur, Corinne A Lutomski, Chi-Hung Lin, William J McKinstry, Christopher J Day, Michael P Jennings, Martin F Jarrold, Johnson Mak

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Chandan KishorInstitute for Glycomics, Griffith University, Gold Coast, QLD 4222, Australia.
Belinda L SpillingsInstitute for Glycomics, Griffith University, Gold Coast, QLD 4222, Australia.
Johana LuhurInstitute for Glycomics, Griffith University, Gold Coast, QLD 4222, Australia.ORCID https://orcid.org/0000-0001-5156-1113
Corinne A LutomskiDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.ORCID https://orcid.org/0000-0001-7509-103X
Chi-Hung LinInstitute for Glycomics, Griffith University, Gold Coast, QLD 4222, Australia.
William J McKinstryCSIRO Manufacturing, Parkville, VIC 3004, Australia.
Christopher J DayInstitute for Glycomics, Griffith University, Gold Coast, QLD 4222, Australia.
Michael P JenningsInstitute for Glycomics, Griffith University, Gold Coast, QLD 4222, Australia.ORCID https://orcid.org/0000-0002-1027-4684
Martin F JarroldDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.ORCID https://orcid.org/0000-0001-7084-176X
Johnson MakInstitute for Glycomics, Griffith University, Gold Coast, QLD 4222, Australia.ORCID https://orcid.org/0000-0002-5229-5707
Griffith University · AUIndiana University Bloomington · USCSIRO Manufacturing · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polarized or precision targeting of protein complexes to their destinations is fundamental to cellular homeostasis, but the mechanism underpinning directional protein delivery is poorly understood. Here, we use the uropod targeting HIV synapse as a model system to show that the viral assembly machinery Gag is copolarized with the intracellular calcium (Ca

Identifiers

PMID35253001
PMCPMC8889552
OpenAlexW4210252477

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.