Evidence map›Paper›PMID 35252949›Full record

ArticleBiological psychiatry global open science2022

Associations between Brain Structural Alterations, Executive Dysfunction, and General Psychopathology in a Healthy and Cross-Diagnostic Adult Patient Sample.

Adrienne L Romer, Diego A Pizzagalli

Open access · goldAbstract read
In one paragraph

Article in Biological psychiatry global open science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  7. MULTIMODAL NEURAL CORRELATES OF CHILDHOOD PSYCHOPATHOLOGY.bioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Neurobiological Clusters Are Associated With Trajectories of Overall Psychopathology in Youth.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023
    Article
  10. Brain Structure Relations With Psychopathology Trajectories in the ABCD Study.Journal of the American Academy of Child and Adolescent Psychiatry · 2023
    Article
  11. Examination of the Factor Structure of Psychopathology in a Mozambican Sample.Clinical psychological science : a journal of the Association for Psychological Science · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Adrienne L RomerCenter for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA, USA.
Diego A PizzagalliCenter for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA, USA.
Harvard University · US

Funding

Neuroimaging Studies of Reward Processing in DepressionR37MH068376 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI Diego A Pizzagalli · 2016 to 2026
$7.4M
Multi level Analysis of Positive Valence Systems Across Mood DisordersR01MH101521 · NIMH · MCLEAN HOSPITAL · PI PIZZAGALLI, DIEGO A · 2013 to 2016
$2.1M
Consortium for Neuropsychiatric Phenomics-Coordinating Center (1 of 8)UL1DE019580 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BILDER, ROBERT M · 2008 to 2011
$1.9M
Replicability, Mechanisms, and Trajectory of Neural Alterations Related to General PsychopathologyF32MH124409 · NIMH · MCLEAN HOSPITAL · PI ROMER, ADRIENNE LYNN · 2020 to 2022
$210k
NIDCR NIH HHS UL1 DE019580NIMH NIH HHS F32 MH124409NIMH NIH HHS R01 MH101521NIMH NIH HHS R37 MH068376
6 · The paper itself

Abstract

backgroundA general psychopathology '

methodsWe conducted hypothesis-driven (i.e., region-of-interest) and exploratory whole-brain structural neuroimaging analyses using data from the Consortium for Neuropsychiatric Phenomics study of 272 adults who met diagnostic criteria for schizophrenia, bipolar disorder, or attention deficit-hyperactivity disorder or were healthy controls. Using structural equation modeling, we examined direct and indirect relations between structural neural alterations (within regions-of-interest and regions identified from exploratory analyses) and

resultsHigher levels of

conclusionsExecutive dysfunction may be one mechanism underlying relations between brain structure and general psychopathology. Replication of VAC structural alterations related to

Indexed as

cerebellumexecutive functiongeneral psychopathologyp factorvisual association cortex

Identifiers

PMID35252949
PMCPMC8896812
OpenAlexW3165911868

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.