Evidence map›Paper›PMID 35252911›Full record

ArticleThe Lancet regional health. Western Pacific2022

Evaluating the public health impact of partial and full tobacco flavour bans: A simulation study.

Zitong Zeng, Alex R Cook, Jacinta I-Pei Chen, Yvette van der Eijk

Abstract read
In one paragraph

Article in The Lancet regional health. Western Pacific, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Impact of Menthol Cigarette Bans: A Systematic Review and Meta-Analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. The methodology of quantitative risk assessment studies.Environmental health : a global access science source · 2024
    Review
  8. The tobacco endgame for the Asia Pacific.Respirology (Carlton, Vic.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zitong ZengSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, MD1 Tahir Foundation Building, 12 Science Drive 2, 117549 Singapore.
Alex R CookSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, MD1 Tahir Foundation Building, 12 Science Drive 2, 117549 Singapore.
Jacinta I-Pei ChenSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, MD1 Tahir Foundation Building, 12 Science Drive 2, 117549 Singapore.
Yvette van der EijkSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, MD1 Tahir Foundation Building, 12 Science Drive 2, 117549 Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTobacco flavours such as menthol and fruits, which appeal to youth, remain unregulated in Western Pacific countries. Our goal was to evaluate the potential impact of tobacco flavour bans in Singapore, which has the region's highest flavoured cigarette market share.

methodsUsing an open-cohort microsimulation model, we estimated the impact of full ban and partial ban (excluding menthol and clove) scenarios versus the status quo (no ban) over a 50-year horizon. We used a Markov chain with four states (never, unflavoured, flavoured and ex-smokers), updating each individual's state across each year. We estimated between-state transition probabilities using Markov chain Monte Carlo, with prior distributions derived from national survey data.

findingsWithout a ban, smoking prevalence gradually increases from 12.7% (2018) to 15.2% (2068). In both ban scenarios, smoking prevalence decreases immediately after the ban: by 1.6% points in the full ban, and 0.4% points in the partial ban scenario. In addition, there is a sustained long-term impact as fewer initiate. In the full ban scenario, smoking prevalence decreases to 10.6% by 2068 with a cumulative gain of over 40,000 QALYs. In the partial ban scenario, it remains stable at 12.5% with a cumulative gain of over 20,000 QALYs. INTERPRETATIONS: A tobacco flavours ban would reap substantial public health benefits in countries that, like Singapore, have a large flavoured cigarette market share, especially with a full ban compared to a partial ban not covering menthol or clove-flavoured cigarettes.

fundingThis study was funded by the Singapore Ministry of Health.

Identifiers

PMID35252911
PMCPMC8891712

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.