Evidence map›Paper›PMID 35252798›Full record

ArticleIJU case reports2022

A case of novel coronavirus disease after combination therapy with nivolumab and ipilimumab for metastatic renal cell carcinoma.

Yu Kijima, Tomokazu Shimizu, Shinya Kato, Eri Sekido, Kana Kano, Makoto Toguchi, Toshihide Horiuchi, Hiroshi Toma, Shoichi Iida, Toshio Takagi

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yu KijimaDepartment of Urology and Transplant Surgery Toda Chuo General Hospital Saitama Japan.ORCID https://orcid.org/0000-0002-5760-445X
Tomokazu ShimizuDepartment of Urology and Transplant Surgery Toda Chuo General Hospital Saitama Japan.
Shinya KatoDepartment of Urology and Transplant Surgery Toda Chuo General Hospital Saitama Japan.
Eri SekidoDepartment of Urology Tokyo Women's Medical University Tokyo Japan.
Kana KanoDepartment of Urology and Transplant Surgery Toda Chuo General Hospital Saitama Japan.
Makoto ToguchiDepartment of Urology Tokyo Women's Medical University Tokyo Japan.
Toshihide HoriuchiDepartment of Urology and Transplant Surgery Toda Chuo General Hospital Saitama Japan.
Hiroshi TomaDepartment of Urology and Transplant Surgery Toda Chuo General Hospital Saitama Japan.
Shoichi IidaDepartment of Urology and Transplant Surgery Toda Chuo General Hospital Saitama Japan.
Toshio TakagiDepartment of Urology Tokyo Women's Medical University Tokyo Japan.ORCID https://orcid.org/0000-0003-1775-0943
Tokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe present a case of novel coronavirus disease-2019 that underwent combination therapy with nivolumab and ipilimumab for metastatic renal cell carcinoma. CASE PRESENTATION: A 50-year-old man complained of anorexia and weight loss. Contrast-enhanced computed tomography revealed a solid mass of 57 mm in diameter with cysts in the right kidney, along with liver, lung, and multiple bone metastases. Computed tomography-guided biopsy of the right kidney was performed, and a diagnosis of clear cell renal cell carcinoma was made. Three weeks after nivolumab and ipilimumab administration, the patient contracted coronavirus disease-2019. Anticoagulation therapy (dalteparin) was administered for 4 days once infection was confirmed, after which dexamethasone was administered for 10 days. The patient survived without experiencing worsened respiratory symptoms.

conclusionWe administered nivolumab and ipilimumab combination therapy as treatment for metastatic renal cell carcinoma. No side effects or immune-related adverse events were observed for a short time.

Indexed as

anticoagulantsCOVID‐19drug‐related side effects and adverse reactionsipilimumabnivolumab

Identifiers

PMID35252798
PMCPMC8888016
OpenAlexW4206778703

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.