Evidence map›Paper›PMID 35252794›Full record

ArticleIJU case reports2022

Combination therapy with radiation and hyperthermia-induced clinical complete response of small cell carcinoma of prostate.

Noriyasu Kawai, Takashi Nagai, Aya Naiki-Ito, Keitaro Iida, Toshiki Etani, Taku Naiki, Shuzo Hamamoto, Atsushi Okada, Taro Murai, Takahiro Yasui

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Complementary and Alternative Therapies in Oncology.International journal of environmental research and public health · 2022
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Noriyasu KawaiDepartment of Nephro-urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.ORCID https://orcid.org/0000-0002-2257-3892
Takashi NagaiDepartment of Nephro-urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Aya Naiki-ItoDepartment of Experimental Pathology and Tumor Biology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Keitaro IidaDepartment of Nephro-urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Toshiki EtaniDepartment of Nephro-urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Taku NaikiDepartment of Nephro-urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.ORCID https://orcid.org/0000-0002-7638-6048
Shuzo HamamotoDepartment of Nephro-urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.ORCID https://orcid.org/0000-0002-9968-7468
Atsushi OkadaDepartment of Nephro-urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.ORCID https://orcid.org/0000-0003-2080-3794
Taro MuraiDepartment of Radiology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.
Takahiro YasuiDepartment of Nephro-urology Graduate School of Medical Sciences Nagoya City University Nagoya Japan.ORCID https://orcid.org/0000-0003-2197-2477
Nagoya City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSmall cell carcinoma of the prostate has a poor prognosis even with standard systemic chemotherapy. We report a case, in which combination therapy with radiation and hyperthermia-induced clinical complete response. CASE PRESENTATION: An 87-year-old man complaining of dysuria was referred to our hospital. Based on magnetic resonance imaging findings and a history of prostate cancer, a prostate biopsy was performed, and small cell carcinoma of the prostate was diagnosed. Whole-pelvis radiation therapy was administered with an additional dose to the prostate; eight cycles of hyperthermia treatment (8 MHz radiofrequency capacitive regional hyperthermia) were administered concurrently. Normalized neuron-specific enolase levels and magnetic resonance imaging confirmed a complete response. A few cancer cells were seen in the post-treatment biopsy specimen, which demonstrated positive immunostaining for heat shock protein 70 and HIKESHI.

conclusionIn this case, small cell carcinoma of the prostate was effectively treated with combined radiation and hyperthermia therapy.

Indexed as

clinical complete responsecombination therapyhyperthermiaradiationsmall cell carcinoma of prostate

Identifiers

PMID35252794
PMCPMC8888022
OpenAlexW4205179713

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.