Evidence map›Paper›PMID 35252766›Full record

ArticleOBM integrative and complimentary medicine2022

Effects of the Phytochemical Combination PB123 on Nrf2 Activation, Gene Expression, and the Cholesterol Pathway in HepG2 Cells.

Brooks M Hybertson, Bifeng Gao, Joe M McCord

Open access · diamondAbstract read
In one paragraph

Article in OBM integrative and complimentary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Cytoprotection against Cadmium by Nrf2-Activating Dietary Phytochemicals.HSOA journal of alternative, complementary & integrative medicine · 2024
    Article
  3. Review
  4. Article
  5. Nutritional and Chemical Composition ofFoods (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Brooks M HybertsonPathways Bioscience, Aurora, CO 80045, USA.
Bifeng GaoPathways Bioscience, Aurora, CO 80045, USA.
Joe M McCordPathways Bioscience, Aurora, CO 80045, USA.
Pathways Behavioral Services · USUniversity of Colorado Anschutz Medical Campus · US

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
Supporting Healthy Aging with a Phytochemical Combination that Acts at Multiple Control Points in the Nrf2 Activation PathwayR43AG053128 · NIA · PATHWAYS BIOSCIENCE, LLC · PI HYBERTSON, BROOKS MICHAEL · 2017 to 2017
$210k
NCI NIH HHS P30 CA046934NIA NIH HHS R43 AG053128
6 · The paper itself

Abstract

There has been a long history of human usage of the biologically-active phytochemicals in

Indexed as

agingcholesterolKEAP1Nrf2nutritionoxidative stress

Identifiers

PMID35252766
PMCPMC8896855
OpenAlexW4206837473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.