Evidence map›Paper›PMID 35252550›Full record

ArticleMolecular & cellular oncology2022

Tumor suppressor pathways shape EGFR-driven lung tumor progression and response to treatment.

Giorgia Foggetti, Chuan Li, Hongchen Cai, Dmitri A Petrov, Monte M Winslow, Katerina Politi

Open access · goldAbstract read
In one paragraph

Article in Molecular & cellular oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Giorgia FoggettiDepartment of Internal Medicine (Medical Oncology), Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0003-1844-1413
Chuan LiDepartments of Biology, Stanford University School of Medicine, Stanford, California, USA.ORCID https://orcid.org/0000-0002-4381-3891
Hongchen CaiDepartment of Genetics, Stanford University School of Medicine, Stanford, California, USA.ORCID https://orcid.org/0000-0002-5921-5773
Dmitri A PetrovDepartments of Biology, Stanford University School of Medicine, Stanford, California, USA.ORCID https://orcid.org/0000-0002-3664-9130
Monte M WinslowDepartment of Genetics, Stanford University School of Medicine, Stanford, California, USA.ORCID https://orcid.org/0000-0002-5730-9573
Katerina PolitiDepartment of Internal Medicine (Medical Oncology), Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0001-6064-4527
Stanford University · USYale Cancer Center · US

Funding

Yale SPORE in Lung Cancer (YSILC): The Biology and Personalized Treatment of Lung CancerP50CA196530 · NCI · YALE UNIVERSITY · PI Shuangge Ma · 2015 to 2026
$31.1M
Mutant EGF Receptor-Dependent Lung Cancer in Human Cell Lines and Transgenic MiceR01CA120247 · NCI · YALE UNIVERSITY · PI POLITI, KATERINA ABIGAIL · 2006 to 2014
$3.8M
Genetic Determinants of Tumor Growth and Drug Sensitivity in EGFR Mutant Lung CancerR01CA263715 · NCI · YALE UNIVERSITY · PI POLITI, KATERINA ABIGAIL, WINSLOW, MONTE MEIER · 2021 to 2025
$2.8M
Unraveling mechanisms of tumor suppression in lung cancerR01CA234349 · NCI · STANFORD UNIVERSITY · PI PETROV, DMITRI, WINSLOW, MONTE MEIER · 2019 to 2023
$2.4M
(PQ4) Quantitative and multiplexed analysis of gene function in cancer in vivoR01CA231253 · NCI · STANFORD UNIVERSITY · PI PETROV, DMITRI, WINSLOW, MONTE MEIER · 2018 to 2022
$2.3M
NCI NIH HHS P50 CA196530NCI NIH HHS R01 CA120247NCI NIH HHS R01 CA231253NCI NIH HHS R01 CA234349NCI NIH HHS R01 CA263715
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EGFRLung cancermultiplexed in vivo genome editingtargeted therapytumor suppressor genes

Identifiers

PMID35252550
PMCPMC8890383
OpenAlexW4205154779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.