Evidence map›Paper›PMID 35252510›Full record

ArticleArthroplasty today2022

Publication Frequency and Google Trends Analysis of Popular Alternative Treatments to Arthritis.

Neil Pathak, Zachary J Radford, Joseph B Kahan, Jonathan N Grauer, Lee E Rubin

Open access · goldAbstract read
In one paragraph

Article in Arthroplasty today, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Neil PathakDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Zachary J RadfordDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Joseph B KahanDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Jonathan N GrauerDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Lee E RubinDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

backgroundPublic interest in alternative, nonoperative treatments for the management of arthritis has increased. Few have been approved by the Food and Drug Administration. The present study aimed to evaluate trends in public and scientific interest in 4 such treatments by assessing Google Trends and publication frequency data, respectively. MATERIAL AND

methodsTurmeric, stem cell therapy, platelet-rich plasma (PRP) therapy, and cannabidiol (CBD) were studied. For 2010-2019, Google Trends data and publication frequency data on PubMed were collected by year for arthritis and each of the 4 therapies. Linear, quadratic, and exponential regressions were applied, and the best model of growth was identified.

resultsFrom 2010 to 2019, Google Trends annual scores for arthritis and turmeric (exponential; R

conclusionRegression analysis indicates that public interest in alternative therapies have had a marked increase. The rise in public interest for CBD, and to a lesser extent, turmeric, stem cell therapy, and PRP, has dramatically outstripped scientific evidence on these therapies. Rigorously designed, clinical studies may be beneficial to keep up with the growing popularity of these treatments, especially CBD.

Indexed as

ArthritisCBDPRPStem cell therapyTurmeric

Identifiers

PMID35252510
PMCPMC8889241
OpenAlexW4214659689

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.