Evidence map›Paper›PMID 35252380›Full record

ArticleFrontiers in cardiovascular medicine2022

Atrial Fibrillation and Depression: A Bibliometric Analysis From 2001 to 2021.

Yuzhen Ai, Yaxuan Xing, Longmei Yan, Dan Ma, Anran Gao, Qiwu Xu, Shan Zhang, Ting Mao, Qiu Pan, Xiaojuan Ma and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  7. N-palmitoyl glycine mediates depression-associated atrial fibrillation via Man1a2-dependent autophagy and NRAP dysregulation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
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  9. A bibliometric analysis of the 50 most cited articles about quality of life in patients with atrial fibrillation.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article
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  16. Bibliometric Insights Into the Evolution of Atrial Fibrillation and Dementia Research 2002-2022.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  17. Article
  18. Review
  19. P2X7 receptor inhibition prevents atrial fibrillation in rodent models of depression.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yuzhen AiXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yaxuan XingXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Longmei YanXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Dan MaXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Anran GaoXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Qiwu XuXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Shan ZhangXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Ting MaoXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Qiu PanXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xiaojuan MaXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Jingchun ZhangXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNXiyuan Hospital · CNBeijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe control of diseases related to atrial fibrillation (AF) may reduce the occurrence of AF, delay progression, and reduce complications, which is beneficial to the prevention and treatment of AF. An increasing number of studies have shown that AF is associated with depression. However, to date, there has not been a bibliometric analysis to examine this field systematically. Our study aimed to visualize the publications to determine the hotspots and frontiers in research on AF and depression and provide guidance and reference for further study.

methodsPublications about AF and depression between 2001 and 2021 were retrieved from the Web of Science Core Collection (WOSCC) database. CiteSpace 5.8. R1, VOSviewer 1.6.16, and Excel 2019 software tools were used to conduct this bibliometric study.

resultsIn total, 159 articles and reviews were analyzed. The number of publications has been increased sharply since 2018. David D. McManus had the largest number of publications. The most prolific country was the USA with 54 publications but the centrality was <0.1. The most prolific institution was Northeastern University. Three clusters were formed based on keywords: The first cluster was composed of atrial fibrillation, depression, anxiety, symptoms, ablation, and quality of life, et al. The second cluster were risk, prevalence, mortality, heart failure, association, et al. While the third cluster included anticoagulation, impact, stroke, management, warfarin, et al. After 2019, stroke and prediction are the keywords with strongest citation bursts.

conclusionResearch on AF and depression is in its infancy. Cooperation and exchanges between countries and institutions must be strengthened in the future. The effect of depression on prevalence and mortality in AF, depression on ablation in AF, and impact of depression on anticoagulation treatment in AF have been the focus of current research. Stroke prevention (including anticoagulant therapy) is the research frontier, which may still be the focus of research in the future.

Indexed as

atrial fibrillationbibliometric analysisCiteSpacedepressionvisual analysis

Identifiers

PMID35252380
PMCPMC8888833
OpenAlexW4212875629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.