Evidence map›Paper›PMID 35252323›Full record

ArticleFrontiers in surgery2022

Preoperative Left Ventricular Energy Loss in the Operating Theater Reflects Subjective Symptoms in Chronic Aortic Regurgitation.

Atsushi Kainuma, Keiichi Itatani, Koichi Akiyama, Yoshifumi Naito, Maki Ishii, Masaru Shimizu, Junya Ohara, Naotoshi Nakamura, Yasufumi Nakajima, Satoshi Numata and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Increased Diastolic Energy Loss Associated with Cardiac Events in Adults with Pulmonary Atresia Suffering from Intact Ventricular Septum.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Atsushi KainumaDepartment of Anesthesiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Keiichi ItataniDepartment of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Koichi AkiyamaDepartment of Anesthesiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yoshifumi NaitoDepartment of Anesthesiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Maki IshiiNorth Medical Center, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Masaru ShimizuDepartment of Anesthesiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Junya OharaDepartment of Anesthesiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Naotoshi NakamuraCenter for Mathematical Modeling and Data Science, Osaka University, Osaka, Japan.
Yasufumi NakajimaDepartment of Anesthesiology and Critical Care, Kansai Medical University, Osaka, Japan.
Satoshi NumataDepartment of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Hitoshi YakuDepartment of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Teiji SawaDepartment of Anesthesiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Kyoto Prefectural University of Medicine · JPKansai Medical University · JPNorth Medical Center · JPOsaka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is currently no subjective, definitive evaluation method for therapeutic indication other than symptoms in aortic regurgitation. Energy loss, a novel parameter of cardiac workload, can be visualized and quantified using echocardiography vector flow mapping. The purpose of the present study was to evaluate whether energy loss in patients with chronic aortic regurgitation can quantify their subjective symptoms more clearly than other conventional metrics.

methodsWe studied 15 patients undergoing elective aortic valve surgery for aortic regurgitation. We divided the patients into symptomatic and asymptomatic groups using their admission records. We analyzed the mean energy loss in one cardiac cycle using transesophageal echocardiography during the preoperative period. The relationships between symptoms, energy loss, and other conventional metrics were statistically analyzed.

resultsThere were seven and eight patients in the symptomatic and asymptomatic groups, respectively. The mean energy loss of one cardiac cycle was higher in the symptomatic group (121 mW/m [96-184]) than in the asymptomatic group (87 mW/m [80-103]) (

conclusionsAn energy loss can quantify patients' subjective symptoms more clearly than other conventional metrics. The small sample size is the primary limitation of our study, further studies assessing larger cohort of patients are warranted to validate our findings.

Indexed as

aortic regurgitation (AR)energy loss (EL)subjective symptomstransesophageal echocardiographyvector flow mapping (VFM)

Identifiers

PMID35252323
PMCPMC8889468
OpenAlexW4213263747

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.