Evidence map›Paper›PMID 35252316›Full record

ReviewFrontiers in nutrition2022

Oxysterols as Reliable Markers of Quality and Safety in Cholesterol Containing Food Ingredients and Products.

Federico Canzoneri, Valerio Leoni, Ginevra Rosso, Davide Risso, Roberto Menta, Giuseppe Poli

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Federico CanzoneriSoremartec Italia Srl, Ferrero Group, Alba, Italy.
Valerio LeoniLaboratory of Clinical Chemistry, ASST Brianza, School of Medicine and Surgery, Hospital of Desio, University of Milano Bicocca, Milan, Italy.
Ginevra RossoSoremartec Italia Srl, Ferrero Group, Alba, Italy.
Davide RissoSoremartec Italia Srl, Ferrero Group, Alba, Italy.
Roberto MentaSoremartec Italia Srl, Ferrero Group, Alba, Italy.
Giuseppe PoliUnit of General Pathology and Physiopathology, Department of Clinical and Biological Sciences, San Luigi Hospital, University of Turin, Turin, Italy.
University of Milano-Bicocca · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholesterol is a lipid of high nutritional value that easily undergoes oxidation through enzymatic and non-enzymatic pathways, leading to a wide variety of cholesterol oxidation products (COPs), more commonly named oxysterols. The major oxysterols found in animal products are 7α-hydroxycholesterol, 7β-hydroxycholesterol, 7-ketocholesterol, 5α,6α-epoxycholesterol, 5β,6β-epoxycholesterol, cholestan-3β,5α,6β-triol, and 25-hydroxycholesterol. They are all produced by cholesterol autoxidation, thus belonging to the non-enzymatic oxysterol subfamily, even if 7α-hydroxycholesterol and 25-hydroxycholesterol are, in part, generated enzymatically as well. A further oxysterol of the full enzymatic origin has recently been detected for the first time in milk of both human and bovine origin, namely 27-hydroxycholesterol. Nowadays, gas or liquid chromatography combined to mass spectrometry allows to measure all these oxysterols accurately in raw and in industrially processed food. While non-enzymatic oxysterols often exhibited

Indexed as

autoxidationcholesterolCOPScytotoxicityfood processingmarkersoxysterolsshelf life

Identifiers

PMID35252316
PMCPMC8890664
OpenAlexW4212949924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.