ArticleFrontiers in nutrition2022
Relationships Between Depressive Symptoms, Dietary Inflammatory Potential, and Sarcopenia: Mediation Analyses.
Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- The association of dietary inflammatory potential with skeletal muscle strength, mass, and sarcopenia: a meta-analysis.Frontiers in nutrition · 2023Pooled it
- The Association between Dietary Inflammatory Index and Aging Biomarkers/Conditions: A Systematic Review and Dose-response Meta-analysis.The journal of nutrition, health & aging · 2023Pooled it
- Pooled it
- Longitudinal association between sarcopenia and comorbidity of mild cognitive impairment and depression among older adults in China: the moderating effect of non-obesity.BMC geriatrics · 2026Article
- Diet-induced inflammation and its association with sarcopenia in an Iranian population: a case-control study.Journal of health, population, and nutrition · 2025Article
- The Intersection of Sarcopenia and Musculoskeletal Pain: Addressing Interconnected Challenges in Aging Care.International journal of environmental research and public health · 2025Review
- Dietary influence on the link between depression and muscle mass and muscle strength: exploring interaction and mediation effects.BMC public health · 2025Article
- Association of the cardiometabolic index with sarcopenia among U.S. adults: NHANES 2011-2018 findings.PloS one · 2025Article
- Causality between Sarcopenia and Depression: A Bidirectional Mendelian Randomization Study.Actas espanolas de psiquiatria · 2024Article
- Association between dietary inflammatory index and energy-adjusted dietary inflammatory index and constipation in US adults.BMC gastroenterology · 2024Article
- Association between triglyceride-glucose index and sarcopenia in patients with chronic inflammatory airway disease.Heliyon · 2024Article
- Bidirectional Association between Sarcopenia and Depressive Symptoms among Chinese Middle- and Older-Aged Adults: Longitudinal Observational Study.Brain sciences · 2024Article
- Effects of household solid fuel use on sarcopenia in middle-aged and older adults: evidence from a nationwide cohort study.Frontiers in public health · 2024Article
- The Mediating Role of Sarcopenia in the Association between Physical Activity and Falls among Chinese Older Adults: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2023Article
- Sarcopenia with Depression Presents a More Severe Disability Than Only Sarcopenia among Japanese Older Adults in Need of Long-Term Care.Medicina (Kaunas, Lithuania) · 2023Article
- Sarcopenia and nervous system disorders.Journal of neurology · 2022Review
- Relationship between leisure-time physical activity and depressive symptoms under different levels of dietary inflammatory index.Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSarcopenia is a major public health problem. Depressive symptoms and dietary inflammatory potential play important roles in the development of sarcopenia. We aimed to disentangle the relationships between depressive symptoms, dietary inflammatory potential, and sarcopenia.
methodsA total of 6,082 participants from the National Health and Nutrition Examination Survey (NHANES) were included in the analyses. Sarcopenia was defined according to the Foundation for the National Institutes for Health (FNIH) criteria. The Depressive symptoms were assessed using the nine-item Patient Health Questionnaire (PHQ-9). Dietary Inflammatory Index (DII) was calculated based on 24-h dietary recall interview. Two sets of mediation models were constructed separately.
resultsDepressive symptoms and DII were associated with sarcopenia, with odds ratios [ORs] (95% CIs) 2.54 (1.27, 5.13) and 1.17 (1.00, 1.37), respectively. DII score mediated the association of depressive symptoms with low muscle mass, explaining a total of 10.53% of the association (indirect effect = 0.004). Depressive symptoms had a significant mediating effects on the association between DII with low muscle mass, explaining a total of 12.50% of the association (indirect effect = 0.001).
conclusionsOur findings suggested that both depressive symptoms and dietary inflammatory potential had direct effects, and indirect effects on low muscle mass, handgrip strength, muscle mass, through each other. It provides important insights into integrated nutritional and psychological intervention strategies in preventing sarcopenia.
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