Evidence map›Paper›PMID 35252249›Full record

ArticleFrontiers in medicine2022

Donor-Related Risk Factors for Graft Decompensation Following Descemet's Stripping Automated Endothelial Keratoplasty.

Sota Nishisako, Takefumi Yamaguchi, Masatoshi Hirayama, Kazunari Higa, Dai Aoki, Chiaki Sasaki, Hisashi Noma, Jun Shimazaki

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sota NishisakoCornea Center and Eye Bank, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Takefumi YamaguchiDepartment of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Masatoshi HirayamaDepartment of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Kazunari HigaCornea Center and Eye Bank, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Dai AokiCornea Center and Eye Bank, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Chiaki SasakiCornea Center and Eye Bank, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Hisashi NomaDepartment of Data Science, The Institute of Statistical Mathematics, Tokyo, Japan.
Jun ShimazakiCornea Center and Eye Bank, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Tokyo Dental College Ichikawa General Hospital · JPThe Institute of Statistical Mathematics · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo identify donor-related risk factors associated with graft endothelial failure and postoperative endothelial cell density (ECD) reduction after Descemet's stripping automated endothelial keratoplasty (DSAEK).

methodsThis was a single-center retrospective study conducted from July 2006-December 2016. We included 584 consecutive eyes (482 patients) that underwent DSAEK for the treatment of laser iridotomy-related bullous keratopathy (192 eyes), pseudophakic bullous keratopathy (137 eyes), regraft (96 eyes), Fuchs' endothelial corneal dystrophy (FECD; 59 eyes) and others (100 eyes). Twenty-three donor- and recipient-related risk factors potentially associated with graft failure and ECD reduction were assessed using Cox hazard models and linear mixed effect models.

resultsThe median age of the patients was 73.5 years (male; 35.6%). After DSAEK, ECD decreased from 2,674 cells/mm

conclusionsPseudophakic status and/or presence of preoperative endothelial folds are the significant donor risk factors for endothelial failure in non-FECD patients.

Indexed as

Descemet's stripping automated endothelial keratoplasty (DSAEK)donor pseudophakic lens statusdonor-related risk factorsnon-fuchs' endothelial corneal dystrophy patientspreoperative endothelial folds

Identifiers

PMID35252249
PMCPMC8889573
OpenAlexW4210409493

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.