Evidence map›Paper›PMID 35252204›Full record

ArticleFrontiers in cell and developmental biology2022

Three-Dimensional Growth of Prostate Cancer Cells Exposed to Simulated Microgravity.

Dorothea Dietrichs, Daniela Grimm, Jayashree Sahana, Daniela Melnik, Thomas J Corydon, Markus Wehland, Marcus Krüger, Randy Vermeesen, Bjorn Baselet, Sarah Baatout and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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  15. Omics Studies of Tumor Cells under Microgravity Conditions.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Dorothea DietrichsDepartment of Microgravity and Translational Regenerative Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Daniela GrimmDepartment of Microgravity and Translational Regenerative Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Jayashree SahanaDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Daniela MelnikDepartment of Microgravity and Translational Regenerative Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Thomas J CorydonDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Markus WehlandDepartment of Microgravity and Translational Regenerative Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Marcus KrügerDepartment of Microgravity and Translational Regenerative Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Randy VermeesenRadiobiology Unit, SCK CEN, Belgian Nuclear Research Centre, Mol, Belgium.
Bjorn BaseletRadiobiology Unit, SCK CEN, Belgian Nuclear Research Centre, Mol, Belgium.
Sarah BaatoutRadiobiology Unit, SCK CEN, Belgian Nuclear Research Centre, Mol, Belgium.
Trine Engelbrecht HybelDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Stefan KahlertInstitute of Anatomy, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Herbert SchulzDepartment of Microgravity and Translational Regenerative Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Manfred InfangerDepartment of Microgravity and Translational Regenerative Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Sascha KoppDepartment of Microgravity and Translational Regenerative Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Otto-von-Guericke University Magdeburg · DEAarhus University · DKBelgian Nuclear Research Centre · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer metastasis has an enormous impact on the mortality of cancer patients. Factors involved in cancer progression and metastasis are known to be key players in microgravity (µ

Indexed as

cytokinescytoskeletonextracellular matrixinterleukinsPAM signalingprostate cancerprostate cancer cells and microgravity

Identifiers

PMID35252204
PMCPMC8893349
OpenAlexW4212824905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.