Evidence map›Paper›PMID 35252164›Full record

ArticleFrontiers in cell and developmental biology2022

Galectin-9 Mediates the Therapeutic Effect of Mesenchymal Stem Cells on Experimental Endotoxemia.

Yiming Zhao, Dingding Yu, Hongda Wang, Wang Jin, Xiang Li, Yonghao Hu, Yafei Qin, Dejun Kong, Guangming Li, Acheampong Ellen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  4. Persistent tailoring of MSC activation through genetic priming.Molecular therapy. Methods & clinical development · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Yiming ZhaoDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Dingding YuDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Hongda WangDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Wang JinDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Xiang LiDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Yonghao HuDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Yafei QinDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Dejun KongDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Guangming LiDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Acheampong EllenDepartment of Pathology, Massachusetts General Hospital, Boston, MA, United States.
Hao WangDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Tianjin Medical University General Hospital · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endotoxemia remains a major cause of mortality in the intensive care unit, but the therapeutic strategy is still lacking. Mesenchymal stem cell (MSC) was reported with a tissue-oriented differentiation ability and an excellent immunoregulatory capacity. However, the immunity signaling pathways that govern MSC modulation effect are not completely understood. In our current study, MSCs (2.5 × 10

Indexed as

endotoxemiagalectin-9immunoregulationlipopolysaccharidemesenchymal stem cell

Identifiers

PMID35252164
PMCPMC8893172
OpenAlexW4213390315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.