ReviewFrontiers in bioengineering and biotechnology2021
The Evolution of Orbital Implants and Current Breakthroughs in Material Design, Selection, Characterization, and Clinical Use.
Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Quality of life with anophthalmia: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Pooled it
- Clinical application of biomaterials in orbital implants: a systematic review.International ophthalmology · 2024Pooled it
- A spatiotemporally programmed bioactive scaffold for orbital reconstruction.Bioactive materials · 2027Article
- Exosomal peptides and proteins in wound healing and skin regeneration.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- A Review of Past Research and Some Future Perspectives Regarding Titanium Alloys in Biomedical Applications.Journal of functional biomaterials · 2025Review
- Article
- [Enucleations, eviscerations and orbital implants in German eye hospitals].Die Ophthalmologie · 2024Article
- Clinical outcomes and complications of a new high-density polyethylene-based spherical integrated porous orbital implant.International ophthalmology · 2024Observational
- Biopolymeric Innovations in Ophthalmic Surgery: Enhancing Devices and Drug Delivery Systems.Polymers · 2024Review
- Tuning zinc content in wollastonite bioceramic endowing outstanding angiogenic and antibacterial functions beneficial for orbital reconstruction.Bioactive materials · 2024Article
- Towards Precision Ophthalmology: The Role of 3D Printing and Bioprinting in Oculoplastic Surgery, Retinal, Corneal, and Glaucoma Treatment.Biomimetics (Basel, Switzerland) · 2024Review
- Automatic data-driven design and 3D printing of custom ocular prostheses.Nature communications · 2024Article
- The Use of Functional Biomaterials in Aesthetic and Functional Restoration in Orbital Surgery.Journal of functional biomaterials · 2024Review
- Optimizing surgical approaches for lacrimal gland adenoid cystic carcinoma to minimize cross-organ invasion.International journal of ophthalmology · 2024Article
- An Orbital Mystery: A Unique Case of an Obsolete Orbital Implant With a Review of Orbital Implant Materials.Cureus · 2022Article
- Optic nerve head: A gatekeeper for vitreous infectious insults?Frontiers in immunology · 2022Article
- Delayed Extrusion of Hydroxyapatite Cement Orbital Floor Implant: A Rare Case Report of Augmentation Failure.Case reports in ophthalmologyArticle
- Sudden Painful Proptosis following Orbital Evisceration: Early Implant Hemorrhage in the Anophthalmic Socket.Journal of current ophthalmologyArticle
- Quality of Life in Patients With Acquired Anophthalmia Using an Ocular Prosthesis.Ophthalmic plastic and reconstructive surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is occasionally essential to surgically remove the damaged eye of the patient in the case of serious oculoorbital injuries, intraocular cancers, and other life-threatening diseases. An orbital implant is placed into the anophthalmic socket after the eye is removed to provide adequate volume reinstatement and revamp the cosmetic look of a normal eye. In the previous few decades, implant design and material selection criteria have progressed from basic nonporous polymeric spheres to devices with more complicated shapes and functions to ensure improved long-term clinical results. Because of their highly interconnected porous design, ceramic and polymeric porous implants have found popularity as a passive framework for fibrovascular ingrowth, with lower obstacle rates and the option of setting to improve prosthetic eye mobility. These materials, however, are not without flaws. The danger of migration and extrusion, infections after surgery, and poor motility transferred to the cosmetic ocular prosthesis are important elements of orbital implants of today. As a result, the development of novel biomaterials with improved functionalities (i.e., antibacterial effect, angiogenesis, and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.